5-Azacytidine | CAS 320-67-2 | Chemical-Suppliers

Element: azacytidine

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C-S » Chemicals » azacytidine-PX72360

Identification

5-Azacytidine

CAS:

320-67-2

EINECS:

206-280-2

Molecular Formula:

C₈H₁₂N₄O₅

MDL:

MFCD00006539

SMILES:

NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@H](O)C1O

Synonym:

5 azc ; 5-ac ; 5-ac-15n4 ; mylosar ; azgr ; u18496 ; 5-azcr ; wr 183027 ; 5-azac ; vidaza

Description

5-Azacytidine is a potent growth inhibitor and a cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. 5-Azacytidine also improves the efficiency of reprogramming of stem cells and induces differentiation of mesenchymal stem cells into cardiomyocytes.

Suppliers

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FUDI Chemical Co. Ltd.

FCC2861144

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI8973588

Shandong Minglang Chemical Co., Ltd

SMC4551820

H&Z Industry Co.,Ltd

HIC2601040

Wuhan PharmChem Co., LTD.

WP325975

Shandong SanYoung Industry Co., Ltd

SSI4551820

JieJie Group Co., Ltd.

JG286858

Guangzhou Topwork Chemical Co., Ltd.

GTC4681872

Xinxiang Aurora Biotechnology Co., Ltd.

XAB5072028

X´ian Taicheng Chem Co., Ltd

XTC3771508

BoomKing Industrial Co.,Limited

BIC4031612

Xiamen Equation Chemical Co.,Ltd

XECC4162080

Sancai Industry Co.,Ltd.

SIC3121248

Fox Chemicals GmbH

FC234702

CSNpharm, Inc.

CSN19354

Wanko Chemical Co., Ltd.

WC312936

Carbone Scientific Co., Ltd.

CS3641092

Acinopeptide Co., Ltd.

A286572

Hefei Hirisun Pharmatech Co., Ltd

HR131339

CM Fine Chemicals

CFC221884

AK Scientific, Inc.

AS247741

DSL Chemicals (Shanghai) Co., Ltd.

C004644

Simagchem Corporation

SC273819

Xingrui Industry Co., Limited

XIL3771508

Capot Chemical Co., Ltd.

14167

Amadis Chemical Company Limited

ACCL4032015

Leap Chem Co., Ltd

LC234702

Santa Cruz Biotechnology, Inc.

221003

Dayang Chem (Hangzhou) Co.,Ltd.

DC4031612

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BLD Pharmatech Ltd

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Prices & Availability

Data is processed

Properties for 5-Azacytidine

Molecular Weight:

244.2 g·mol−1

Density:

2.08 g/cm³(lit.)

Melting point:

226-232 °C (dec.)(lit.)

Boiling point:

534.5° C (lit.) at 760 mmHg

Solubility:

Soluble in water (50 mg/ml), DMSO (49 mg/ml at 25° C), ethanol (~30 mg/ml), methanol, and DMF (~30 mg/ml).

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed
R45 - May cause cancer
R46 - May cause inheritable genetic damage

Safety Codes:

S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use

Hazard Symbols:

Storage temperature :

2-8°C

Alternative Distributors of [5-Azacytidine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified