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Desloratadine

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Formula: C19H19ClN2
CAS: 100643-71-8
search Element: desloratadine

Identification

Structural Formula
Desloratadine
CAS:
100643-71-8
EINECS:
Molecular Formula:
C19H19ClN2
MDL:
MFCD00871949
SMILES:
C1CC2=C(C=CC(=C2)Cl)C(=C3CCNCC3)C4=C1C=CC=N4
Synonym:


Description

Desloratadine is a potent and selective histamine H1-receptor agonist with a half life of 21-24 hours. Experiments suggest that this compound also exerts antioxidant effects in vitro. Other studies show that H1-receptor binding by desloratadine is reversible and that, over time, desloratadine dissociates from membrane H1-recepters. Desloratadine has also demonstrated the ability to block ICAM-1 upregulation and NFκB activation in primary bronchial and transformed respiratory epithelial cells in vitro.


Suppliers

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Shandong Minglang Chemical Co., Ltd
SMC4551820
H&Z Industry Co.,Ltd
HIC2601040
Aozeal Certified Standards (AOCS), Inc.
D0012.00
Ambeed, Inc.
A129917
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8973588
Inke S.A.
IS117351
Inke S.A.
IS117351
Quzhou Rundong Chemical Co., Ltd.
QRC4291716
Aecochem Corp.
AC182546
CSNpharm, Inc.
CSN10775
Hangzhou Keying Chem Co., Ltd.
HKC3901560
Hangzhou Lingrui Chemical Co., Ltd.
HLC4551820
Wanko Chemical Co., Ltd.
WC312936
Sigma-Aldrich International GmbH
SI4161248
CM Fine Chemicals
CFC221884
AK Scientific, Inc.
AS247741
Xingrui Industry Co., Limited
XIL3771508
Leap Chem Co., Ltd
LC234702
Santa Cruz Biotechnology, Inc.
202133
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Sancai Industry Co.,Ltd.
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Carbone Scientific Co., Ltd.
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Simagchem Corporation
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Xiamen Equation Chemical Co.,Ltd
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Aozeal Certified Standards (AOCS), Inc.
R0050.02

Prices & Availability




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Properties for Desloratadine

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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

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Alternative Distributors of [Desloratadine]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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