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Hydroxyurea

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Formula: CH4N2O2
CAS: 127-07-1
search Element: hydroxyurea

Identification

Structural Formula
Hydroxyurea
CAS:
127-07-1
EINECS:
204-821-7
Molecular Formula:
CH4N2O2
MDL:
MFCD00007943
SMILES:
NC(=O)NO
Synonym:
hu ; droxia ; hydura ; nhy ; hydreia ; sq1089 ; hydrea ; hidrix ; siklos ; oxyure


Description

Hydroxyurea is a demonstrated antineoplastic agent, which is believed to block DNA replication by inhibiting R1 and R2 (ribonucleotide reductase) via destruction of the free radical at the enzymes active site. Induces apoptosis of in vitro myelogenous leukemia lymphocytes, and the phosphorylation of FADD and p53.


Suppliers

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Ambeed, Inc.
A145474
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI7593036
H&Z Industry Co.,Ltd
HIC220880
WG Critical Care, LLC
WCCL2311155
Indofine Chemical Co, Inc.
Bio-216
Serva Electrophoresis GmbH
SE286858
Daming Changda Co., Ltd.
DC264792
CSNpharm, Inc.
CSN16113
Wanko Chemical Co., Ltd.
WC264792
scienTEST - bioKEMIX GmbH
S-B2751100
AK Scientific, Inc.
AS209627
Xingrui Industry Co., Limited
XIL3191276
Leap Chem Co., Ltd
LC198594
Santa Cruz Biotechnology, Inc.
29061
Dayang Chem (Hangzhou) Co.,Ltd.
DC3411364
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Alfa (A Johnson Matthey Company)
A5121536
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Acros Organics BVBA
AOB3041216
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Sigma-Aldrich International GmbH
SI19205760
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BLD Pharmatech Ltd
BP16204860

Prices & Availability




Data is processed


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Properties for Hydroxyurea

Molecular Weight:
76.05 g·mol−1
Density:
1.46 g/cm3 (Predicted)
Melting point:
135-140 °C
Boiling point:
244.72° C at 760 mmHg (Predicted)
Solubility:
H2O: 50 mg/mL
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Hazard Statements

GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R40 - Limited evidence of a carcinogenic effect
R46 - May cause inheritable genetic damage
R61 - May cause harm to the unborn child
R63 - Possible risk of harm to the unborn child
Safety Codes:
S22 - Do not breathe dust
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
Hazard Symbols:
T, Xn
Hazard symbol T Hazard symbol Xn
Storage temperature :
2-8°C
RID/ADR certification :
2811
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Alternative Distributors of [Hydroxyurea]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Inter-Chemical Ltd. | Standard Chem. & Pharm. Co., Ltd | Rongkang Industry Co.,Ltd - (NSTU Chemicals Hanggzhou Co.,) | Molekula GmbH | Hallochem Pharma Co., Ltd. | Nanjing King-Pharm Co., Ltd. | Xiang Ding Chemical International Co., Ltd | ABCR GmbH & Co. KG | Hongda Group Limited | Ningbo Pangs Chem Int'l Co., Ltd. | TCI Europe NV | Shiva Chemicals & Pharmaceuticals Services Ltd. | New Dragon Industrial Co., Ltd | Jinan Bangda Chemical Co.,Ltd | ChengDu KaiXin Technology Development Co., Ltd. | Discovery Fine Chemicals Limited | Jinan Wedo Industrial Co., Ltd. | Shanghai AOKChem Group Limited | TRUST&WE Co., Ltd. | Shiva Chemicals and Pharmaceuticals Services Limited | Suzhou Rovathin Pharmatech Co., Ltd | Lanospharma Laboratories Co., Ltd. | Shanghai Hanhong Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Jinjiangchem Corporation | Suzhou Sibian Chemical Technology Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | API Vanguard | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Aopharm | BOC Sciences | Wolves R&D Chemicals | Jinan Haohua Industry Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Pfaltz & Bauer, Inc. | Gihi Chemicals Co., Limited | Xiamen Hisunny Chemical Co., Ltd. | Angel Synthesis Co., Ltd | scienTEST | Clearsynth Canada INC. | Haihang Industry Co., Ltd.

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