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BX 795

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Formula: C23H26IN7O2S
CAS: 702675-74-9
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Identification

Structural Formula
BX 795
CAS:
702675-74-9
EINECS:
Molecular Formula:
C23H26IN7O2S
MDL:
SMILES:
C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I
Synonym:


Description

BX 795 is shown to be a specific and potent inhibitor of IκB kinase ε (IKKε), phosphoinositide 3-kinase 1 (PDK1), and TANK-binding kinase 1 (TBK1). These protein kinases regulate production of type 1 interferons during certain infections. BX 795 has been suggested in studies to block nuclear translocation, phosphorylation, and transcriptional activity of interferon regulatory factor 3. This in turn blocks the production of interferon-β in macrophages. Further experiments have shown that BX 795 is capable of blocking the autophosphorylation of overexpressed TBK1 and IκKε


Suppliers

Santa Cruz Biotechnology, Inc.
281689
Dayang Chem (Hangzhou) Co.,Ltd.
DC186744
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CAS equal suppliers

BX795
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Amadis Chemical Company Limited
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N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
Hangzhou MolCore BioPharmatech Co.,Ltd.
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N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
Leap Chem Co., Ltd
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N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
Xingrui Industry Co., Limited
XIL48720194880

Prices & Availability




Data is processed


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Properties for BX 795

Molecular Weight:
591.47 g·mol−1
Density:
~1.6 g/cm3 (Predicted)
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Safety & Transport Information

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Alternative Distributors of [BX 795]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

ShangHai Biochempartner Co., Ltd. | Shanghai Witofly Chemical Co., Ltd.

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