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YM201636

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Formula: C25H21N7O3
CAS: 371942-69-7
search Element: ym201636

Identification

Structural Formula
YM201636
CAS:
371942-69-7
EINECS:
Molecular Formula:
C25H21N7O3
MDL:
MFCD16038303
SMILES:
C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)NC(=O)C6=CN=C(C=C6)N
Synonym:
YM 201636 ; ; 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide


Description

YM201636 is a potent inhibitor of phosphatidylinositol phosphate kinase PIP5KIII (PIKfyve). PIKfyve has been noted to synthesize phosphatidylinositol 3,5-bisphosphate and is also reported to be involved in sorting endosomal transport. YM201636 displays the ability to inhibit basal and insulin-activated 2-deoxyglucose uptake and has also been shown to completely block insulin-dependent activation of class IA PI 3-kinase.


Suppliers

Aea.ltd
A56112
Amadis Chemical Company Limited
ACCL2481240
Leap Chem Co., Ltd
LC144432
Santa Cruz Biotechnology, Inc.
204193
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CAS equal suppliers

YM 201636
Capot Chemical Co., Ltd.
22459
YM-201636
Dayang Chem (Hangzhou) Co.,Ltd.
DC2791116
YM-201636
Santa Cruz Biotechnology, Inc.
SCB2701080
YM-201636
CSNpharm, Inc.
CSN15968
3-Pyridinecarboxamide, 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-
Hangzhou MolCore BioPharmatech Co.,Ltd.
MC111409

Prices & Availability




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Properties for YM201636

Molecular Weight:
467.48 g·mol−1
Density:
~1.4 g/cm3 (Predicted)
Melting point:
327.48° C
Boiling point:
745.93° C (Predicted)
Solubility:
Soluble in DMSO (1 mg/mL), 1:2 DMSO:PBS (pH 7.2) (~0.3 mg/mL), and DMF (~10 mg/mL).
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Alternative Distributors of [YM201636]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Excenen Pharmatech Co., Ltd. | D&P Global Chemical Co., Ltd

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Mol File:
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MSDS:
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