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YC-1

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Formula: C19H16N2O2
CAS: 170632-47-0
search Element:

Identification

Structural Formula
YC-1
CAS:
170632-47-0
EINECS:
Molecular Formula:
C19H16N2O2
MDL:
MFCD06407798
SMILES:
OCC1=CC=C(O1)C1=NN(CC2=CC=CC=C2)C2=CC=CC=C12
Synonym:


Description

YC-1 can activate platelet soluble GCS (guanylate cylcase) indepedent of nitric oxide activation. It has the ability to inhibit aggregation of platelets and increase the platelets cAMP and cGMP content, as well as act as an antithrombotic compound. Data shows that the highest activation of GCS is observed in the presence of YC-1. The compound can suppress HIF-1 α activity in neonatal rat ventricular myocytes. Research shows that GCS activators (YC-1) might have the ability to activate the sGC/cGMP/PKG pathway and influence the activation of Ras/Raf-1/p44/42 MAPK. YC-1 is an activator of GCS (guanylate cylcase). YC-1 is an inhibitor of HIF-1 α.


Suppliers

Aea.ltd
A2856
Amadis Chemical Company Limited
ACCL124620
Santa Cruz Biotechnology, Inc.
202856
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Prices & Availability




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Properties for YC-1

Molecular Weight:
304.34 g·mol−1
Density:
~1.2 g/cm3 (Predicted)
Melting point:
110-113° C
Boiling point:
~522.17° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (12 mg/ml), methanol (5 mg/ml), ethanol (50 mM), DMF (~20 mg/ml), 5:2 DMSO:PBS(pH 7.2) (~10 ug/ml), and dichloromethane. Insoluble in water.
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Alternative Distributors of [YC-1]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | D&P Global Chemical Co., Ltd

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