K 858 | CAS 72926-24-0 | Chemical-Suppliers

Element:

Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification Properties Suppliers Prices & Availability Get Quick Quote

C-S » Chemicals » -PX69519

Identification

K 858

CAS:

72926-24-0

EINECS:

Molecular Formula:

C₁₃H₁₅N₃O₂S

MDL:

MFCD00181155

SMILES:

CC(=O)NC1=NN(C(=O)C)C(C)(S1)c1ccccc1

Synonym:

Acetamide, N-(4-acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)-

Description

K 858 is an ATP-uncompetitive mitotic kinesin Eg5 inhibitor, which does not effect microtubule dynamics. Studies on HCT116 cells indicate that K 858 causes mitotic arrest, cell growth inhibition, and activates caspase-3. It is also believed that K858 inhibits the growth of cancer cells. Studies suggest that K 858 is not neurotoxic in motor coordination. Furthermore, K 858 can be a beneficial tool because unlike similar compounds that inhibit Eg5, K 858 does not form breaks in double stranded DNA.

Suppliers

Santa Cruz Biotechnology, Inc.

300856

Get Quick Quote

CAS equal suppliers

K858

CSNpharm, Inc.

CSN18408

K-858

ShangHai Biochempartner Co., Ltd.

BCP17181

K-858

Excenen Pharmatech Co., Ltd.

EX-A822

N-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide

Finipharma Ltd

F817616352

Prices & Availability

Data is processed

Properties for K 858

Molecular Weight:

277.34 g·mol−1

Density:

~1.27 g/cm³ (Predicted)

Solubility:

Soluble in DMSO (100 mM), and ethanol (10 mM).

Safety & Transport Information

coming up soon

Alternative Distributors of [K 858]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

Downloads

Mol File:

-/-

MSDS:

-/-