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CH 55

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Formula: C24H28O3
CAS: 110368-33-7
search Element:

Identification

Structural Formula
CH 55
CAS:
110368-33-7
EINECS:
Molecular Formula:
C24H28O3
MDL:
MFCD06798383
SMILES:
CC(C)(C)C1=CC(=CC(=C1)C(=O)C=CC2=CC=C(C=C2)C(=O)O)C(C)(C)C
Synonym:
4-[(e)-3-(3,5-di-tert-butylphenyl)-3-oxo-1-propenyl]benzoic acid ; 4-[(e)-3-[3,5-bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid ; benzoic acid, 4-(3-(3,5-bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)-, (e)- ; ch 55 ; (e)-4-(3-(3,5-bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)benzoic acid ; 4-[(e)-3-[3,5-bis(tert-butyl)phenyl]-3-oxo-1-propenyl]benzoic acid ; 4-[(1e)-3-[3,5-bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid


Description

CH 55 is a highly potent, synthetic retinoid that has high affinity for RAR-α and RAR-β receptors. CH 55 is also noted to have low affinity for cellular retinoic acid binding protein (CRABP). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50 = 1 nM).


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Properties for CH 55

Molecular Weight:
364.48 g·mol−1
Density:
1.09 g/cm3 (Predicted)
Melting point:
205.02° C (Predicted)
Boiling point:
509.48° C at 760 mmHg (Predicted)
Solubility:
Soluble in ethanol (50 mM), and DMSO (100 mM).
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Safety & Transport Information

Storage temperature :
Store at RT
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Alternative Distributors of [CH 55]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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