SU 16f | CAS 251356-45-3 | Chemical-Suppliers

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C-S » Chemicals » -PX72495

Identification

SU 16f

CAS:

251356-45-3

EINECS:

Molecular Formula:

C₂₄H₂₂N₂O₃

MDL:

MFCD03452699

SMILES:

CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=C(C=C(C=C3)C4=CC=CC=C4)NC2=O

Synonym:

Description

SU 16f is a selective PDGFRβ inhibitor with an IC₅₀=10nM. In vitro studies demonstrate that SU 16f also inhibits HUVEC and NIH3T3 cell proliferation with an IC₅₀=0.11μM. In addition, SU 16f displays 14 fold selectivity towards PDGFRβ compared to Flk-1 (VEGFR2), 229-fold over Flg (FGFR1) and 10000-fold over EGFR. SU 16f is an inhibitor of Flk-1.

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Santa Cruz Biotechnology, Inc.

204307

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Properties for SU 16f

Molecular Weight:

386.44 g·mol−1

Density:

~1.29 g/cm³ (Predicted)

Solubility:

Soluble in DMSO (100 mM). Insoluble in ethanol.

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Alternative Distributors of [SU 16f]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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