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PQ401

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Formula: C18H16 Cl N3 O2
CAS: 196868-63-0
search Element: pq401

Identification

Structural Formula
PQ401
CAS:
196868-63-0
EINECS:
Molecular Formula:
C18H16 Cl N3 O2
MDL:
MFCD00160558
SMILES:
COc1ccc(Cl)cc1NC(=O)Nc1cc(C)nc2ccccc12
Synonym:
IGF-1R Inhibitor II, N-(5-Chloro-2-methoxyphenyl)-N'-(2-methylquinolin-4-yl)urea ; PQ401 ; Urea,N-(5-chloro-2-methoxyphenyl)-N'-(2-methyl-4-quinolinyl)-


Description

PQ401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation. The mechanism of inhibition likely involves indirect blocking of ATP binding. PQ401 also decreases IGF-1R-dependent tumor cell growth in vitro.


Suppliers

Aea.ltd
A3570
Pharmacore Co., Limited
PL115345
Hefei Hirisun Pharmatech Co., Ltd
HR060456
Leap Chem Co., Ltd
LC90270
Santa Cruz Biotechnology, Inc.
221738
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CAS equal suppliers

PQ 401
ShangHai Biochempartner Co., Ltd.
BCP06474
1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
Hangzhou MolCore BioPharmatech Co.,Ltd.
MC443020
1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
Capot Chemical Co., Ltd.
34003
N-(5-chloro-2-methoxyphenyl)-Nmy-(2-methylquinolin-4-yl)urea
Amadis Chemical Company Limited
ACCL1302065100
N-(5-chloro-2-methoxyphenyl)-Nmy-(2-methylquinolin-4-yl)urea
BLD Pharmatech Ltd
BP756022680
IGF-1R Inhibitor II, N-(5-Chloro-2-methoxyphenyl)-Nμ-(2-methylquinolin-4-yl)urea
Chemieliva Pharmaceutical Co., Ltd.
CP35700107100

Prices & Availability




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Properties for PQ401

Molecular Weight:
341.796 g·mol−1
Density:
1.370±0.06 g/cm3 (20 °C 760 Torr)
Solubility:
Soluble in DMSO or Ethanol
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Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
Safety Codes:
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
2-8°C
RID/ADR certification :
UN 2811 6.1/PG 3
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Alternative Distributors of [PQ401]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

D&P Global Chemical Co., Ltd

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MSDS:
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