C75 | CAS 218137-86-1 | Chemical-Suppliers

Element:

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C-S » Chemicals » -PX75425

Identification

C75

CAS:

218137-86-1

EINECS:

Molecular Formula:

C₁₄H₂₂O₄

MDL:

MFCD03426157

SMILES:

CCCCCCCC[C@@H]1[C@H](C(=C)C(=O)O1)C(=O)O

Synonym:

c75(4-methylene-2-octyl-5-oxo-tetrahydro-furan-3-carboxylicacid) ; trans-tetrahydro-3-methylene-2-oxo-5-n-octyl-4-furancarboxylic acid ; c75 ; trans-4-carboxy-5-octyl-3-methylenebutyrolactone ; 3-carboxy-4-octyl-2-methylenebutyrolactone

Description

C75 is an inhibitor of fatty acid synthase (FAS) reducing food intake and body weight in mice. Exhibits irreversible slow-binding biphasic inactivation of fatty acid synthase. Downregulates neuropeptide Y and Agouti-related protein expression. Has been proposed to activate CPT-1 activity in liver and adipose tissue, leading to increased fatty acid oxidation and energy production. Shows significant antitumor activity in human breast cancer cells. Suppresses DNA replication and induces apoptosis. FAS inhibition by C75 leads to a dramatic accumulation of the CDK inhibitor p27KIP1 from cytosol to cell nuclei.

Suppliers

Santa Cruz Biotechnology, Inc.

202511

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Prices & Availability

Data is processed

Properties for C75

Molecular Weight:

254.32 g·mol−1

Solubility:

DMSO: 18 mg/mL

Safety & Transport Information

Storage temperature :

2-8°C

Alternative Distributors of [C75]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

SYNCHEM OHG | Shanghai Elittes Organics Co., Ltd.

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