TN-16 | CAS 33016-12-5 | Chemical-Suppliers

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C-S » Chemicals » -PX76093

Identification

TN-16

CAS:

33016-12-5

EINECS:

Molecular Formula:

C₁₉H₁₈N₂O₂

MDL:

MFCD02684017

SMILES:

C/C(=C1/C(=O)C(NC1=O)CC2=CC=CC=C2)/NC3=CC=CC=C3

Synonym:

nsc 239274 ; 3-[1-(phenylamino)ethylidene]-5-(phenylmethyl)-2,4-pyrrolidinedione ; 3-(1-anilinoethylidene)-5-benzylpyrrolidine-2,4-dione ; 3-(anilinoethylidene)-5-benzylpyrrolidine-2,4-dione ; 2,4-pyrrolidinedione, 3-(1-(phenylamino)ethylidene)-5-(phenylmethyl)- (9ci) ; tn-16 ; 2,4-pyrrolidinedione, 3-(1-anilinoethylidene)-5-benzyl- (8ci)

Description

TN-16 is a synthetic antitumor drug that blocks microtubule assembly by binding to the colchicine site of Tubulin. TN-16 prevents stabilization of microtubules in Paclitaxel-treated cells. The compound also blocks the cell cycle in M phase.

Suppliers

Santa Cruz Biotechnology, Inc.

204347

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Prices & Availability

Data is processed

Properties for TN-16

Molecular Weight:

306.36 g·mol−1

Density:

1.25 g/cm³ (Predicted)

Melting point:

182-185° C

Boiling point:

532.69° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (25 mg/ml), warm ethanol (12.5 mg/ml), and DMF.

Safety & Transport Information

Risk Codes:

R43 - May cause sensitisation by skin contact
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment

Safety Codes:

S36/37 - Wear suitable protective clothing and gloves
S60 - This material and its container must be disposed of as hazardous waste
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet

Hazard Symbols:

Xi, N

Storage temperature :

2-8 °C

Alternative Distributors of [TN-16]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences

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Mol File:

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MSDS:

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