M 344 | CAS 251456-60-7 | Chemical-Suppliers

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C-S » Chemicals » -PX77017

Identification

M 344

CAS:

251456-60-7

EINECS:

Molecular Formula:

C₁₆H₂₅N₃O₃

MDL:

MFCD03453554

SMILES:

CN(C)C1=CC=C(C=C1)C(=O)NCCCCCCC(=O)NO

Synonym:

4-(dimethylamino)-n-[7-(hydroxyamino)-7-oxoheptyl]-benzamide, ms 344, d237, n-hydroxy-7-(4-dimethylaminobenzoyl)-aminoheptanamide ; 4-(diethylamino)-n-[7-(hydroxyamino)-7-oxoheptyl]benzamide ; ms 344 ; ms 344 ; n-hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide ; histone deacetylase inhibitor iii ; 4-dimethylamino-n-(6-hydroxycarbamoylhexyl)-benzamide ; 4-(dimethylamino)-n-[7-(hydroxyamino)-7-oxoheptyl]-benzamide ; m344 ; m 344 (enzyme inhibitor) ; benzamide,4-(dimethylamino)-n-[7-(hydroxyamino)-7-oxoheptyl]- ; ms 344, d237

Description

M344 is a potent HDAC inhibitor (IC₅₀ = 100 nM), with selectivity for HDAC6 over HDAC1. M344 induces terminal cell differentiation and causes an increase in hyperacetylated histone H4. It also induces cell cycle arrest and apoptosis in human endometrial and ovarian cancer cells.

Suppliers

Santa Cruz Biotechnology, Inc.

203124

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CAS equal suppliers

M344

Ambeed, Inc.

A201295

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CSNpharm, Inc.

CSN12888

4-Dimethylamino-N-(6-hydroxycarbamoylhexyl)benzamide

Leap Chem Co., Ltd

LC28088424

4-Dimethylamino-N-(6-hydroxycarbamoylhexyl)benzamide

Finipharma Ltd

F21844368

N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide

Salsbury Chemicals, Inc.

SC499214976

N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide

Finetech Industry Limited

FIL520020800

4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide

TCI Chemicals (India) Pvt. Ltd.

D4188

7-{[4-(Dimethylamino)phenyl]formamido}-N-hydroxyheptanamide

Dayang Chem (Hangzhou) Co.,Ltd.

DC1097443896

Benzamide, 4-(dimethylamino)-n-[7-(hydroxyamino)-7-oxoheptyl]-

Angene International Limited

AGN-PC-0JK6Q6

Prices & Availability

Data is processed

Properties for M 344

Molecular Weight:

307.39 g·mol−1

Density:

1.137 g/cm3

Melting point:

161°C

Boiling point:

558.27° C (Predicted)

Solubility:

Soluble in DMSO (62 mg/ml at 25° C), ethanol (4 mg/ml), DMF (~25 mg/ml at 25° C), and water (<1 mg/ml at 25° C).

Safety & Transport Information

Storage temperature :

2-8°C

Alternative Distributors of [M 344]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Sino Rarechem Labs Co. Ltd.

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MSDS:

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