Adenosine 3′,5′-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt | CAS 30275-80-0

Element: monophosphate adenosine benzoyl cyclic sodium prime prime salt

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C-S » Chemicals » adenosine-cyclic-monophosphate-benzoyl-sodium-salt-PX68245

Identification

Adenosine 3′,5′-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt

CAS:

30275-80-0

EINECS:

Molecular Formula:

C₁₇H₁₆ N₅ O₇ P

MDL:

MFCD01074967

SMILES:

C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=CN=C4NC(=O)C5=CC=CC=C5)O)OP(=O)(O1)[O-].[Na+]

Synonym:

Benzamide,N-(9-b-D-ribofuranosyl-9H-purin-6-yl)-,cyclic hydrogen phosphate (8CI) ; 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin,adenosine deriv. ; N6-Benzoyl-3',5'-AMP ; N6-Benzoyl-cAMP ; N6-Benzoyl-cyclic AMP ; N6-Benzoyladenosine cyclic 3',5'-phosphate ; Adenosine, N-benzoyl-,cyclic 3',5'-(hydrogen phosphate)

Description

Adenosine 3′,5′-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt is a potent cell permeable activator of both type 1 and type 2 PKA, which are cAMP dependent. Studies indicate that Adenosine 3′,5′-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt interacts with PKA by binding to site 2 on the regulatory subunit. As a result of PKA activation Adenosine 3′,5′-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt increases cytosolic calcium ion concentration. In addition, this compound can cross over cell membranes in various cells due to its lipophilic nature. (Note: 10μmol=~4.6mg)

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Adenosine 3′,5′-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt

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Properties for Adenosine 3′,5′-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt

Molecular Weight:

433.312 g·mol−1

Density:

1.95 g/cm3

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Adenosine 3′,5′-cyclic Monophosphate, N6-Benzoyl-, Sodium Salt