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N-alpha-t-Butyloxycarbonyl-beta,beta-dimethyl-L-proline

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Formula: C12H21NO4
CAS: 174060-98-1

Identification

Structural Formula
N-alpha-t-Butyloxycarbonyl-beta,beta-dimethyl-L-proline
CAS:
174060-98-1
EINECS:
Molecular Formula:
C12H21NO4
MDL:
Synonym:
(s)-n-boc-3,3-dimethylpyrrolidine-2-carboxylic acid ; boc-(2s)-3,3-dimethyl-2-pyrrolidenecarboxylic acid ; (s)-1-(tert-butoxycarbonyl)-3,3-dimethylpyrrolidine-2-carboxylic acid ; (2s)-3,3-dimethyl-1,2-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester


Description

beta,beta-Dimethylation of amino acids stabilizes appropriate peptides towards digestion by proteases. Reference: Benzyl 2-Cyano-3,3-Dimethyl-1-pyrrolidinecarboxylate, a Versatile Intermediate for the Synthesis of 3,3-Dimethylproline Derivatives; Jesus R. Medina, Charles W. Blackledge, Karl F. Erhard, Jeffrey M. Axten, and William H. Miller; J. Org. Chem. 2008; 73: 3946-3949. DOI: 10.1021/jo7027163.


Suppliers

Iris Biotech GmbH
BAA2870
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Prices & Availability




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Properties for N-alpha-t-Butyloxycarbonyl-beta,beta-dimethyl-L-proline

Molecular Weight:
243.3 g·mol−1
Density:
1.117
Melting point:
121-123° C
Solubility:
Soluble in Chloroform and Dimethyl Sulfoxide
Physical Description:
white solid
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Safety & Transport Information

Storage temperature :
-20°C Freezer
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Alternative Distributors of [N-alpha-t-Butyloxycarbonyl-beta,beta-dimethyl-L-proline]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Shanghai AOKChem Group Limited | Clearsynth Canada INC.

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