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Ambroxol hydrochloride

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Formula: C13H18Br2N2O.HCl
CAS: 23828-92-4

Identification

Structural Formula
Ambroxol hydrochloride
CAS:
23828-92-4
EINECS:
245-899-2
Molecular Formula:
C13H18Br2N2O.HCl
MDL:
MFCD00078932
SMILES:
C1CC(CCC1NCC2=CC(=CC(=C2N)Br)Br)O.Cl
Synonym:
ambron ; fluixol ; antobron ; abramen ; frenopect ; ankisol ; ambril ; mucolear ; bluibron ; duramucal


Description

Ambroxol hydrochloride is a small molecule expectorant and mucolytic agent with antioxidant and antiinflammatory effects. Ambroxol stimulates the secretion of surfactant which decreases mucus adhesion to the bronchial lining and produces expectorant effects. The antioxidant effects of Ambroxol are well demonstrated, where lipid peroxidation initiated by t-butyl hydroperoxide or doxorubicin is suppressed in the presence Ambroxol, and scavenging of hydroxyl radicals and cellular superoxide radical anions is also observed. Ambroxol produces antiinflammatory effects by blocking the expression of proinflammatory messengers, inhibiting the release of histamine from mast cells and the generation of cytokines and interleukins. Ambroxol hydrochloride is an inhibitor of Sodium Channel Protein.


Suppliers

H&Z Industry Co.,Ltd
HIC8803520
Shandong SanYoung Industry Co., Ltd
SSI15406160
Nantong Xindao Biotech Ltd
NXB11444576
Aozeal Certified Standards (AOCS), Inc.
A0034.00
Ambeed, Inc.
A118627
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI303612144
European Manufacturers Assoc. Inc.
EMA14965984
B.M.P. Bulk Medicines & Pharmaceuticals GmbH
BBMP19369680
Jai Radhe Sales
JRS6602640
INNOCHEM
I352704
X´ian Taicheng Chem Co., Ltd
XTC12765104
BoomKing Industrial Co.,Limited
BIC13645456
Caesar & Loretz GmbH
CL8802640
Xiamen Equation Chemical Co.,Ltd
XECC14087040
Sancai Industry Co.,Ltd.
SIC10564224
Aecochem Corp.
AC6161848
scienTEST - bioKEMIX GmbH
S-B11004400
AK Scientific, Inc.
AS8362508
Simagchem Corporation
SC9242772
Xingrui Industry Co., Limited
XIL12765104
Leap Chem Co., Ltd
LC7922376
Santa Cruz Biotechnology, Inc.
200816
Dayang Chem (Hangzhou) Co.,Ltd.
DC13645456
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Exim Corporation
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CSNpharm, Inc.
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Huateng Pharmaceutical Co.,Ltd
80016236
trans-4-[(2-Amino-3,5-dibromobenzyl)amino]cyclohexanol hydrochloride
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Prices & Availability




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Properties for Ambroxol hydrochloride

Molecular Weight:
414.56 g·mol−1
Melting point:
233-234.5 °C
Boiling point:
468.6° C at 760 mmHg
Solubility:
Soluble in methanol, water (~5 mg/ml), ethanol (~5 mg/ml), and DMSO (50 mM). Insoluble in ether.
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Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
Safety Codes:
S36 - Wear suitable protective clothing
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
2-8°C
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Alternative Distributors of [Ambroxol hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Zibo Panxin Pharmaceutical Co., Ltd. | Ningbo Zhengrun Chemicals Co., Ltd. Exp. Dept. | Molekula GmbH | Hallochem Pharma Co., Ltd. | Argosi International Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | Jiangsu Guotai International Group Co., Ltd. | Xiang Ding Chemical International Co., Ltd | Haining Boosten Import & Export Co., Ltd. | Shaanxi Hanjiang Pharmaceutical Group Co., Ltd. | Shaanxi Hanjiang Pharmaceutical Group Co., Ltd. | Abtonsmart Chemicals Co., Ltd. | New Dragon Industrial Co., Ltd | Hefei Photochem Trading Co., Ltd | Formax Chemicals Co., Ltd. | Long Island Pharmaceutical & Chemical Co. Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Suzhou Rovathin Pharmatech Co., Ltd | Hangzhou Pharma & Chem Co. Ltd. | Shanghai Boyle Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Ningbo Hi-Tech Biochemicals Co., Ltd. | Bichem Lab Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Orex Pharma Pvt. Ltd | Pharmfar Co., Ltd. | Watson International Ltd | Suzhou Bichal Biological Technology Co., Ltd. | BOC Sciences | Apollo Healthcare Resources | Changzhou Sunsanta Trading Co., Ltd | Jinan Haohua Industry Co., Ltd. | Trademax Phamaceuticals & Chemicals Co., Ltd. | Beijing Mediking Biopharm Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Hangzhou Neway Chemicals Co., Ltd. | scienTEST | Gihi Chemicals Co., Limited | Clearsynth Canada INC.

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