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7-Amino-4-methylcoumarin

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Formula: C10H9NO2
CAS: 26093-31-2

Identification

Structural Formula
7-Amino-4-methylcoumarin
CAS:
26093-31-2
EINECS:
247-454-8
Molecular Formula:
C10H9NO2
MDL:
MFCD00006868
SMILES:
CC1=CC(=O)OC2=C1C=CC(N)=C2
Synonym:
7-amc ; h-mca ; akos b014362 ; coumarin 120 ; coumarin 440 ; c 120 ; nsc 45796 ; amc ; cumarin120 ; c120


Description

7-Amino-4-methylcoumarin (AMC) is a well-known laboratory reagent employed in the preparation of fluorogenic AMC-based substrates for the detection of proteolytic enzyme activity. AMC has been utilized as a fluorescent probe to analyze glycoproteins' monosaccharides and N-linked oligosaccharides via chromatography and has been used as a laser dye. Recent research shows that AMC was extracted from an endophytic Xylaria fungal species and exhibited strong antibacterial and antifungal activities in vitro against Aspergillus, Candida, Escherichia, Staphylococcus, Salmonella and Vibrio species, among others. This product is also useful as a reference standard in enzymatic assays.


Suppliers

Ambeed, Inc.
A371201
BLD Pharmatech Ltd
BP8642592
Indofine Chemical Co, Inc.
020547
Indofine Chemical Co, Inc.
ICC12484992
Xiamen Equation Chemical Co.,Ltd
XECC15367680
Hangzhou Zhongqi Chem Co., Ltd
HZC14405760
Synthon-Chemicals GmbH & Co. KG
ST01790
CSNpharm, Inc.
CSN10955
scienTEST - bioKEMIX GmbH
S-B12004800
Carbone Scientific Co., Ltd.
CS13444032
CM Fine Chemicals
CFC8163264
AK Scientific, Inc.
AS9122736
Simagchem Corporation
SC10083024
Capot Chemical Co., Ltd.
11097
Santa Cruz Biotechnology, Inc.
202429
Dayang Chem (Hangzhou) Co.,Ltd.
DC14885952
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CAS equal suppliers

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Acinopeptide Co., Ltd.
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Leap Chem Co., Ltd
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Jinan Honestpharm Co., Ltd
JH12483744
7-Amino-4-methylcoumarin, 98%
Alfa (A Johnson Matthey Company)
A18565568
7-amino-4-methyl-chroman-2-one
Manchester Organics Limited
B27681
7-Amino-4-methylcoumarin (AMC)
Molekula
22061681
7-Amino-4-methyl-2H-chromen-2-one
Hangzhou MolCore BioPharmatech Co.,Ltd.
CS11356
7-Amino-4-methyl-2H-chromen-2-one
Xingrui Industry Co., Limited
XIL382815312
7-Amino-4-methylcoumarin, 98%, pure
Acros Organics BVBA
AOB19957980
7-Amino-4-methylcoumarin [for HPLC Labeling]
TCI Chemicals (India) Pvt. Ltd.
M0760

Prices & Availability




Data is processed


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Properties for 7-Amino-4-methylcoumarin

Molecular Weight:
175.18 g·mol−1
Density:
1.28 g/cm3 (Predicted)
Melting point:
223-226 °C(lit.)
Boiling point:
378.26° C at 760 mmHg (Predicted)
Solubility:
Soluble in acetone (10 mg/ml), DMSO (10 mg/ml), and DMF.
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S37/39 - Wear suitable gloves and eye/face protection
Hazard Symbols:
Xi, Xn
Hazard symbol Xn Hazard symbol Xi
Storage temperature :
2-8°C
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Alternative Distributors of [7-Amino-4-methylcoumarin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | ABCR GmbH & Co. KG | Gihi Chemicals Co., Limited | Watson International Ltd | 3B Scientific Corporation | Bona Chemical Co., Limited | GLSynthesis Inc. | TCI Europe NV | Ubichem PLC | Molekula GmbH | Chem-Impex International, Inc. | Organix UK | scienTEST | Jinan Haohua Industry Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Chengdu Qiaofeng Technological Development Co., Ltd. | AOKBIO Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd.

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