D(-)-2-Amino-5-phosphonovaleric acid (D-AP5) | CAS 79055-68-8

Element: phosphonovaleric amino acid

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Identification

D(-)-2-Amino-5-phosphonovaleric acid (D-AP5)

CAS:

79055-68-8

EINECS:

Molecular Formula:

C₅H₁₂NO₅P

MDL:

MFCD00078839

SMILES:

C(C[C@H](C(=O)O)N)CP(=O)(O)O

Synonym:

d-norvaline,5-phosphono- ; d-apv ; d-aminophosphonovaleric acid ; (r)-5-phosphono-2-aminovaleric acid ; death associated protein 5 ; (r)-ap-5 ; d-2-amino-5-phosphonopentanoic acid ; d-(-)-2-amino-5-phosphonopentanoicacid ; (2r)-2-amino-5-phosphonovaleric acid ; d-2-amino-5-phosphonovaleric acid ; eif4g2 ; 5-phosphono-d-norvaline ; (r)-2-amino-5-phosphonovaleric acid ; d-ap-5 ; (-)-2-amino-5-phosphonopentanoicacid ; (r)-2-amino-5-phosphonopentanoicacid ; d-ap5 ; if4g2 ; (-)-2-amino-5-phosphonovaleric acid

Description

D(-)-2-Amino-5-phosphonovaleric acid (D-AP5) is a selective antagonist of the NMDA receptor. D(-)-2-Amino-5-phosphonovaleric acid is described to antagonize amino acid-induced synaptic excitations, blocking L-aspartate and dorsal root-evoked spinal neuron excitation, without affecting cholinergic excitation induced by exogenous acetylcholine administration. Evoked electrical activity of neurons is suppressed by D(-)-2-Amino-5-phosphonovaleric acid antagonism of motoneuronal depolarizations at the NMDA_R. The (+)-stereoisomer of D(-)-2-Amino-5-phosphonovaleric acid demonstrates considerably diminished NMDA_R activity as compared to this (-)-isomer.

Suppliers

Santa Cruz Biotechnology, Inc.

200434

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Prices & Availability

Data is processed

Properties for D(-)-2-Amino-5-phosphonovaleric acid (D-AP5)

Molecular Weight:

197.13 g·mol−1

Density:

1.529 g/cm3

Melting point:

245-246 °C

Boiling point:

482.1 °C at 760 mmHg

Flash point:

245.4 °C

Physical Description:

white fine crystalline powder

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

Store at RT

Alternative Distributors of [D(-)-2-Amino-5-phosphonovaleric acid (D-AP5)]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Jinan Haohua Industry Co., Ltd. | Salsbury Chemicals, Inc.,

Downloads

Mol File:

-/-

MSDS:

-/-

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