3-Amino-1,2,4-triazole | CAS 61-82-5

Element: triazole amino

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C-S » Chemicals » amino-triazole-PX69130

Identification

3-Amino-1,2,4-triazole

CAS:

61-82-5

EINECS:

200-521-5

Molecular Formula:

C₂H₄N₄

MDL:

MFCD00005230

SMILES:

C1=NNC(=N1)N

Synonym:

vorox ; tr2 ; psctk ; azolan ; 3-at ; at ; ata(r) ; imd1 ; amerol ; xla

Description

3-Amino-1,2,4-triazole is a small molecule irreversible inhibitor of catalase, an enzyme responsible for converting cellular H₂O₂ into H₂O and O₂. Impeding the natural clearance of H₂O₂ from the cell by catalase has proven useful in studies investigating free radical-mediated damage of cardiac tissue in ischemia. 3-Amino-1,2,4-triazole also shows inhibition of imidazoleglycerol-phosphate dehydratase (HIS3) activity, which interrupts the biosynthesis of histidines. When 3-Amino-1,2,4-triazole is diazotized, the resulting 3-Diazo-1,2,4-triazole is shown to react specifically with tryptophan at acidic pH, presenting a method for determining the tryptophan content of proteins.

Suppliers

Krada CPS Industry S.L

KCIS9684840

Wuhan PharmChem Co., LTD.

WP11003300

Shandong SanYoung Industry Co., Ltd

SSI15406160

Connect Chemicals GmbH

CC9682904

Kowa American Corp.

KAC8363344

Sancai Industry Co.,Ltd.

SIC10564224

Hangzhou Lingrui Chemical Co., Ltd.

HLC15406160

scienTEST - bioKEMIX GmbH

S-B11004400

AK Scientific, Inc.

AS8362508

DSL Chemicals (Shanghai) Co., Ltd.

C001885

Xingrui Industry Co., Limited

XIL12765104

Santa Cruz Biotechnology, Inc.

202016

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Angene International Limited

AGN-PC-0ODI4W

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Hangzhou MolCore BioPharmatech Co.,Ltd.

CS22032

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Biesterfeld Spezialchemie GmbH

BS22506750

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CM Fine Chemicals

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Merck Schuchardt OHG

MSO15006000

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Key Organics Limited

PS-9367

3-Amino-1H-1,2,4-triazole, 95%

Acros Organics BVBA

AOB17106840

3-Amino-1H-1,2,4-triazole, 96%

Alfa (A Johnson Matthey Company)

A28808640

Prices & Availability

Data is processed

Properties for 3-Amino-1,2,4-triazole

Molecular Weight:

84.08 g·mol−1

Density:

1.138

Melting point:

150-153 °C(lit.)

Boiling point:

322.2-373.2° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (280 g/l) at 20° C, methanol, ethanol, chloroform, and ethyl acetate (slightly). Insoluble in ether, and acetone.

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

GHS08
Health hazard

Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A, 1B, 2
Carcinogenicity, categories 1A, 1B, 2
Reproductive toxicity, categories 1A, 1B, 2
Specific target organ toxicity following single exposure, categories 1, 2
Specific target organ toxicity following repeated exposure, categories 1, 2
Aspiration hazard, categories 1, 2

GHS09
Environmental hazard

Acute hazards to the aquatic environment, category 1
Chronic hazards to the aquatic environment, categories 1, 2
Environmental toxicity, categories 1, 2

Safety & Transport Information

Risk Codes:

R40 - Limited evidence of a carcinogenic effect
R48/22 - Harmful: danger of serious damage to health by prolonged exposure if swallowed
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R61 - May cause harm to the unborn child
R63 - Possible risk of harm to the unborn child

Safety Codes:

S13 - Keep away from food, drink and animal foodstuffs
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet

Hazard Symbols:

Xn, N, T

Storage temperature :

-20°C

RID/ADR certification :

UN 3077 9 / PG 3

Alternative Distributors of [3-Amino-1,2,4-triazole]

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