Trioxsalens, also known as psoralens, are physiological photosensitizing agents historically used to alter human skin pigmentation. At the molecular level, psoralens intercalate into double-stranded DNA. Irradiation induces monosubstitution of pyrimidine bases. If efficiency is high, double substitution and bridging will occur. Designed to bind tightly within the DNA helix to improve substitution yields during irradiation. Inactivates DNA and RNA viruses, including HIV-1, by inducing nucleic acid cross-linking followed by UV irradiation.
Properties for 4'-Aminomethyltrioxsalen hydrochloride
Molecular Weight:
293.748 g·mol−1
Solubility:
Soluble in Water (1 mg/ml) and DMSO (2 mg/ml)
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Safety & Transport Information
Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed R34 - Causes burns R40 - Limited evidence of a carcinogenic effect
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S27 - Take off immediately all contaminated clothing S36 - Wear suitable protective clothing S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
C
Storage temperature :
2-8°C
RID/ADR certification :
UN 1759 8 / PG 2
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Alternative Distributors of [4'-Aminomethyltrioxsalen hydrochloride]
Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.