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Anisomycin

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Formula: C14H19NO4
CAS: 22862-76-6
search Element: anisomycin
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Identification

Structural Formula
Anisomycin
CAS:
22862-76-6
EINECS:
245-269-7
Molecular Formula:
C14H19NO4
MDL:
MFCD00077650
SMILES:
CC(=O)O[C@@H]1[C@H](CN[C@@H]1CC2=CC=C(C=C2)OC)O
Synonym:
4-beta))-alph ; anisomycin ; aids-031977 ; nsc76712 ; wuningmeisu c ; nsc147340 ; antibioticpa-106 ; flagecidin ; aids031977 ; anisomycin, streptomyces griseolus


Description

Anisomycin is a phenylpyrolidine derivative shown to strongly activate the stress-induced MAP kinases JNK and p38. This activity results in the induction of the immediate-early genes: c-Fos, c-Jun, Fos B, Jun B and Jun D, and enhanced phosphorylation of p54/nrb, ATF-2, ERK, Caldesmon, IRS-1 and IRS-2. This compound behaves as a true signaling agonist, and has been implicated to play an important role in hyperosmolarity and UV-stimulated responses. Anisomycin has also been shown to increase the phosphorylation of p70 S6 kinase α.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6902760
+
CSNpharm, Inc.
CSN10317
Hangzhou Lingrui Chemical Co., Ltd.
HLC3501400
+
Finetech Industry Limited
FIL2501000
+
BOC Sciences
BS120360
+
Amadis Chemical Company Limited
ACCL3101550
+
Santa Cruz Biotechnology, Inc.
3524
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CAS equal suppliers

Wuningmeisu C
Leap Chem Co., Ltd
LC4681404
Wuningmeisu C
Finipharma Ltd
F364728
Anisomycin, 97%
Alfa (A Johnson Matthey Company)
A4801440
anisomycin from streptomyces griseolus
Indofine Chemical Co, Inc.
Bio-510
Anisomycin (from streptomyces griseolus)
Carbone Scientific Co., Ltd.
CS448013440
Anisomycin, 10mg/mL in DMSO, sterile-filtered
Alfa (A Johnson Matthey Company)
A864025920

Prices & Availability




Data is processed


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Properties for Anisomycin

Molecular Weight:
265.3 g·mol−1
Density:
~1.21 g/cm3 (Predicted)
Melting point:
140-141 C
Boiling point:
398.72° C at 760 mmHg
Solubility:
methanol: 20 mg/mL, clear, colorless to faintly yellow
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Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(b)
Hazard Symbols:
T, Xn
Hazard symbol T Hazard symbol Xn
Storage temperature :
2-8°C
RID/ADR certification :
UN 3462 6.1 / PG 3
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Alternative Distributors of [Anisomycin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Molekula GmbH | Discovery Fine Chemicals Limited | SYNCHEM OHG | Cfm Oskar Tropitzsch GmbH | Wolves R&D Chemicals | Fermentek Ltd. | Jinan Haohua Industry Co., Ltd. | Clearsynth Canada INC.

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