Apocynin | CAS 498-02-2 | Chemical-Suppliers

Element: apocynin

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C-S » Chemicals » apocynin-PX66672

Identification

Apocynin

CAS:

498-02-2

EINECS:

207-854-5

Molecular Formula:

C₉H₁₀O₃

MDL:

MFCD00008747

SMILES:

CC(=O)C1=CC(=C(C=C1)O)OC

Synonym:

acetoguaiacon ; nsc 2146 ; acetoguaicone ; acetoguaiacone ; apocynine ; apocynin ; acetovanyllon ; acetovanilone ; nsc 209524 ; acetovanillon

Description

Apocynin is a methoxy-substituted catechol that is commonly used as an inhibitor of Mox and Nox (NADPH oxidase) (IC₅₀=10 μM). Because of Abocynin's inhibition of NADPH oxidase, ROS production is also inhibited. Studies show the compound's ability to decrease superoxide generation in bovine pulmonary arteries as well as neutrophils and macrophages (10 mM). In experimental rats, apocynin has displayed anti-inflammatory activity and can improve endothelial function by reducing oxidative stress and improved NO bioavailability. Reportedly prevents phagocytosis of MBP (myelin) by macrophages. Also has proven to be a useful product for studying NO-regulated processes in plants.

Suppliers

Ambeed, Inc.

A113062

Aozeal Certified Standards (AOCS), Inc.

A0082.00

CSNpharm, Inc.

CSN12681

Santa Cruz Biotechnology, Inc.

203321

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CAS equal suppliers

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Haihang Industry Co., Ltd.

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Autech Industry Co.,Limited

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Dayang Chem (Hangzhou) Co.,Ltd.

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INDAM Inc.

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Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

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Hangzhou Keying Chem Co., Ltd.

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Nantong Xindao Biotech Ltd

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Acetovanillone, 98%

Acros Organics BVBA

AOB3611444

4-Hydroxy-3-methoxyacetophenone

Merck Schuchardt OHG

MSO12404960

3-Methoxy-4-Hydroxy Acetophenone

Hangzhou J&H Chemical Co., Ltd.

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Xiamen Equation Chemical Co.,Ltd

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Simagchem Corporation

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Indofine Chemical Co, Inc.

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DSL Chemicals (Shanghai) Co., Ltd.

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TCI Chemicals (India) Pvt. Ltd.

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Capot Chemical Co., Ltd.

3315

4'-Hydroxy-3'-methoxyacetophenone

Frinton Laboratories

FR-0823

4'-Hydroxy-3'-methoxyacetophenone

Ascender Chemical Co.,Ltd

ACC16506600

1-(4-Hydroxy-3-methoxyphenyl)ethanone

Hangzhou MolCore BioPharmatech Co.,Ltd.

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BLD Pharmatech Ltd

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Alfa (A Johnson Matthey Company)

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Angene International Limited

AGN-PC-0JK65U

Prices & Availability

Data is processed

Properties for Apocynin

Molecular Weight:

166.17 g·mol−1

Density:

1.16 g/cm³

Melting point:

112-115 °C(lit.)

Boiling point:

263-265 °C17 mm Hg(lit.)

Flash point:

>230 ºF

Solubility:

Soluble in ethanol (100 mM), chloroform, ether, hot water, benzene, ethyl acetate, and DMSO (100 mM). Insoluble in Petroleum ether.

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

Refrigerator

Alternative Distributors of [Apocynin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Frinton Laboratories | Carl Roth GmbH + Co KG | Jinan Haohua Industry Co., Ltd. | Clearsynth Canada INC.

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