Aprepitant | CAS 170729-80-3 | Chemical-Suppliers

Element: aprepitant

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C-S » Chemicals » aprepitant-PX70267

Identification

Aprepitant

CAS:

170729-80-3

EINECS:

Molecular Formula:

C₂₃H₂₁F₇N₄O₃

MDL:

MFCD08277635

SMILES:

C[C@@H](O[C@H]1OCCN(CC2=NNC(=O)N2)[C@H]1C1=CC=C(F)C=C1)C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F

Synonym:

mk 0869 aprepitant ; mk-0869 ; emend ; aprepirant ; aprepitant ; ono 7436 ; aprepitant(mk-0869) ; aprepitant, >=99% ; 5-[[(2r,3s)-2-[(1r)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3h-1, ; 5-(((2r,3s)-2-((r)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1h-1,2,4-triazol-3(2h)-one

Description

Aprepitant is a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes show that it is metabolized primarily by CYP3A4 with minor metabolism by CYP2C19 and CYP1A2.

Suppliers

FUDI Chemical Co. Ltd.

FCC220880

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6902760

Shandong Ench Chemical Co.,Ltd

SECC3001500

H&Z Industry Co.,Ltd

HIC200800

Aea.ltd

A70140

Aozeal Certified Standards (AOCS), Inc.

A0067.00

JieJie Group Co., Ltd.

JG220660

Inke S.A.

IS90270

Guangzhou Topwork Chemical Co., Ltd.

GTC3601440

Chemvon Biotechnology Co. Ltd.

CBC3001200

Arcadia Biotechnology

AB210630

Xiamen Equation Chemical Co.,Ltd

XECC3201600

Sancai Industry Co.,Ltd.

SIC240960

CSNpharm, Inc.

CSN10324

Hangzhou Lingrui Chemical Co., Ltd.

HLC3501400

Wanko Chemical Co., Ltd.

WC240720

Finetech Industry Limited

FIL2501000

Carbone Scientific Co., Ltd.

CS280840

Hefei Hirisun Pharmatech Co., Ltd

HR011169

Simagchem Corporation

SC210630

Xingrui Industry Co., Limited

XIL2901160

BOC Sciences

BS120360

Amadis Chemical Company Limited

ACCL3101550

Santa Cruz Biotechnology, Inc.

207299

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CAS equal suppliers

MK-0869

Excenen Pharmatech Co., Ltd.

EX-A212

MK-0869

Aea.ltd

A4998

Aprepitant - Labeled d4

Santa Cruz Biotechnology, Inc.

sc-353012

Aprepitant;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one

3B (Wuhan) Scientific Corporation

3117216351648

Prices & Availability

Data is processed

Properties for Aprepitant

Molecular Weight:

534.4266624 g·mol−1

Melting point:

244-246 °C

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Storage temperature :

-20 °C Freezer

Alternative Distributors of [Aprepitant]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified