Atorvastatin Lactone | CAS 125995-03-1

Element: atorvastatin lactone

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C-S » Chemicals » atorvastatin-lactone-PX71089

Identification

Atorvastatin Lactone

CAS:

125995-03-1

EINECS:

Molecular Formula:

C₃₃H₃₃FN₂O₄

MDL:

MFCD00899262

SMILES:

CC(C)C1=C(C(=C(N1CC[C@@H]2C[C@H](CC(=O)O2)O)C3=CC=C(C=C3)F)C4=CC=CC=C4)C(=O)NC5=CC=CC=C5

Synonym:

diepoxide atorvastatin lactone diepoxide ; atorvastatin calcium impurity d ; (3r,5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-yl]-3,5-dihydroxyheptanoic acid 1,5-lactone ; (4r,6r)-6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl}-4-hydroxytetrahydro-2h-pyran-2-one ; atorvastatin d-lactone ; atorvastatin epimp h (usp rch) ; atorvastatin impurity h ; atorvastatin lactone ; atorvastatin ep impurity h ; 1-[2-[[(2r)-tetrahydro-4?-hydroxy-6-oxo-2h-pyran]-2?-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,n-diphenyl-1h-pyrrole-3-carboxamide

Description

Atorvastatin Lactone is a metabolite of Atorvastin acid, which is an inhibitor of HMG-CoA reductase. By affecting Atorvastatin acid action, Atorvastatin Lactone prevents inhibition of P-glycoprotein mediated Rhodamine 123 transport in cells. Studies suggest that Atorvastatin is also a potent scavenger for free radicals and prevents toxic effects of Gentamycin (sc-357362) by inhibiting NF-κB and MAPK signaling pathways.

Suppliers

Aea.ltd

A280560

Hangzhou Lingrui Chemical Co., Ltd.

HLC14005600

Wanko Chemical Co., Ltd.

WC9602880

Simagchem Corporation

SC8402520

Xingrui Industry Co., Limited

XIL11604640

Capot Chemical Co., Ltd.

29319

Leap Chem Co., Ltd

LC7202160

Santa Cruz Biotechnology, Inc.

207307

Dayang Chem (Hangzhou) Co.,Ltd.

DC12404960

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Simagchem Corporation

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5-(4-Fluorophenyl)-2-(1-methyl-ethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide

Xiamen Equation Chemical Co.,Ltd

XECC82080410400

Prices & Availability

Data is processed

Properties for Atorvastatin Lactone

Molecular Weight:

540.63 g·mol−1

Melting point:

103-106°C

Solubility:

DMF, DMSO, ethyl acetate, methanol

Safety & Transport Information

Storage temperature :

-20°C Freezer, Under Inert Atmosphere

Alternative Distributors of [Atorvastatin Lactone]

Producers or manufacturers change the product range from time to time. The following companies
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