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R-(+)-Baclofen (free base)

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Formula: C10H12ClNO2
CAS: 69308-37-8
search Element: baclofen base free

Identification

Structural Formula
R-(+)-Baclofen (free base)
CAS:
69308-37-8
EINECS:
Molecular Formula:
C10H12ClNO2
MDL:
MFCD01321057
SMILES:
C1=CC(=CC=C1C(CC(=O)O)CN)Cl
Synonym:
(βr)-β-(aminomethyl)-4-chlorobenzenepropanoic acid ; (r)-4-amino-3-(4-chlorophenyl)butyric acid ; l-baclofen ; (r)-4-amino-3-(4-chlorophenyl)butanoic acid ; 4-azanyl-3-(4-chlorophenyl)butanoic acid ; arbaclofen ; r-(+)-baclofen (free base) ; d-baclofen ; stx 209 ; (r)-baclofen


Description

R-(+)-Baclofen (free base) is a selective GABAB receptor agonist. GABAB receptors are metabotropic receptors which produce slow inhibitory signals. By manipulating GABAB receptor activity using Baclofen, a variety of functions are studied including synaptic transmissions and antinociception events.


Suppliers

Santa Cruz Biotechnology, Inc.
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Prices & Availability




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Properties for R-(+)-Baclofen (free base)

Molecular Weight:
213.66 g·mol−1
Melting point:
171-174 °C
Solubility:
Soluble in 1M HCl (50mg/ml) or DMSO.
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Storage temperature :
Store at RT
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Alternative Distributors of [R-(+)-Baclofen (free base)]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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