BAPTA/AM | CAS 126150-97-8 | Chemical-Suppliers

Element: bapta

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C-S » Chemicals » bapta-PX77021

Identification

BAPTA/AM

CAS:

126150-97-8

EINECS:

Molecular Formula:

C₃₄H₄₀N₂O₁₈

MDL:

MFCD00036696

SMILES:

CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)C1=CC=CC=C1OCCOC1=CC=CC=C1N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O

Synonym:

tetrakis(acetoxymethyl) 1,2-bis(2-aminophenoxy)ethane-n,n,n',n'-tetraacetate ; 1,2-bis (2-aminophenoxy)ethane-n,n,n',n'-tetraacetic acid, tetraacetoxymethyl ester ; bapta-am ; 1,2-bis(o-aminophenoxy)ethane-n,n,n',n'-tetraacetic acid tetra(acetoxymethyl) ester ; 1,2-bis(2-aminophenoxy)ethane-n,n,n'',n''-tetraacetic acid
tetrakis(acetoxymethyl ester) ; o,o'-bis(2-aminophenyl)ethyleneglycol-n,n,n',n'-tetraaceticacid,tetraacetoxymethylester ; 1,2-bis(2-aminophenoxy)ethane-n,n,n,n-tetraacetic acid acetoxymethyl ester(bapta-am) ; 1,2-bis(2-aminophenoxy)ethane-n,n,n,n-tetraacetic acid acetoxymethyl ester ; 1,2-bis(2-aminophenoxy)ethane-n,n,n',n'-tetraacetic acid tetrakis(acetoxy-methyl) ester ; bapta am, >=98%

Description

BAPTA/AM [1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester)] is a non-fluorescent, membrane-permeable form of BAPTA. Whereas the BAPTA, Free acid is not cell permeable and is only useful for manipulating extracellular Ca²⁺ levels, BAPTA/AM can be used with a wide variety of cells, where it is hydrolyzed by cytosolic esterases and trapped intracellularly. Experiments have shown that BAPTA/AM abolishes vitamin D₃-induced increase in intracellular Ca²⁺, and may induce inactivation of protein kinase C. Has also been shown to inhibit thapsigargin-induced apoptosis in rat thymocytes. This product is a high quality and sensitive compound for calcium signaling studies, investigation of signal transduction and apoptotic cascades, and neuroscience research.

Suppliers

Aea.ltd

A112224

Zehao Industry Co., Ltd.

ZI3841152

Santa Cruz Biotechnology, Inc.

202488

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Tetrakis(acetoxymethyl) 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetate

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1,2-bis (2-Aminophenoxy)ethane-N,N,N',N'-tetraacetic acid, tetraacetoxymethyl ester

Haihang Industry Co., Ltd.

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1,2-bis-(2-Aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester)

Haihang Industry Co., Ltd.

HI2262067860

Prices & Availability

Data is processed

Properties for BAPTA/AM

Molecular Weight:

764.68 g·mol−1

Density:

1.35 g/cm³ (Predicted)

Melting point:

86-90 °C

Boiling point:

796.09° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (25 mg/ml), chloroform, DMF (25 mg/ml), and 100% ethanol (5 mg/ml, warm).

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

-20°C

Alternative Distributors of [BAPTA/AM]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Jinan Great Chemical Co., Ltd. | BOC Sciences | Jinan Haohua Industry Co., Ltd.