β-Estradiol | CAS 50-28-2 | Chemical-Suppliers

Element: estradiol

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C-S » Chemicals » beta-estradiol-PX81799

Identification

β-Estradiol

CAS:

50-28-2

EINECS:

200-023-8

Molecular Formula:

C₁₈H₂₄O₂

MDL:

MFCD00003693

SMILES:

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O

Synonym:

menest ; bardiol ; cimara ; systen ; macrol ; climara ; evex ; altrad ; e(sub2) ; evorel

Description

β-Estradiol is an endogenous estrogenic hormone receptor (ER) agonist (K_i values are 0.12 and 0.13 nM for ERα and ERβ respectively). Also high affinity ligand at membrane estrogen GPR30 receptors. β-Estradiol is an activator of PI 3-kinase.

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Estradiol 17b (17b-estradiol;1,3,5[10]-estratriene-3,17b-diol,3,17b-Dihydroxy-1,3,5[10]-estratriene, Estra-1,3,5(10)-triene-3,17-diol, beta-Estradiol)

United States Biological

E3550

Prices & Availability

Data is processed

Properties for β-Estradiol

Molecular Weight:

272.38 g·mol−1

Density:

~1.2 g/cm³ (Predicted)

Melting point:

178-179 °C(lit.)

Boiling point:

~445.9° C at 760 mmHg (Predicted)

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36 - Irritating to eyes
R40 - Limited evidence of a carcinogenic effect
R45 - May cause cancer
R60 - May impair fertility
R61 - May cause harm to the unborn child
R63 - Possible risk of harm to the unborn child
R64 - May cause harm to breast-fed babies

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use

Hazard Classes:

6.1

Hazard Symbols:

T, Xn, F

Storage temperature :

2-8°C

RID/ADR certification :

2811

Alternative Distributors of [β-Estradiol]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified