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β-Secretase Inhibitor IV

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Formula: C31H38N4O5S
CAS: 797035-11-1

Identification

Structural Formula
β-Secretase Inhibitor IV
CAS:
797035-11-1
EINECS:
Molecular Formula:
C31H38N4O5S
MDL:
SMILES:
C[C@H](C1=CC=CC=C1)NC(=O)C2=CC(=CC(=C2)N(C)S(=O)(=O)C)C(=O)N[C@@H](CC3=CC=CC=C3)[C@@H](CNC4CC4)O
Synonym:
1,3-benzenedicarboxamide, n1-[(1s,2r)-3-(cyclopropylamino)-2-hydroxy-1-(phenylmethyl)propyl]-5-[methyl(methylsulfonyl)amino]-n3-[(1r)-1-phenylethyl]- ; n-((1s,2r)-1-benzyl-3-cyclopropylamino-2-hydroxy-propyl)-5-(methanesulfonyl-methyl-amino)-n'-((r)-1-phenyl-ethyl)-isophthalamide ; 1,3-benzenedicarboxamide, n1-[(1s,2r)-3-(cyclopropylamino)-2-hydroxy-1-(phenylmethyl)propyl]-5-[methyl(methylsulfonyl)amino]-n3-[(1r)-1-phenylethyl]- ; beta-secretase inhibitor iv ; ?-secretase inhibitor iv ; n1-((2s,3r)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl)-5-(n-methylmethylsulfonamido)-n3-((r)-1-phenylethyl)isophthalamide ; bace-1 inhibitor


Description

β-Secretase Inhibitor IV, a cell-permeable isophthalamide compound containing a hydroxyethylamine motif which binds to BACE-1 active site and potently blocks its proteolytic activity. The compound displays greater selectivity over other aspartyl proteases. β-Secretase Inhibitor IV is an inhibitor of BACE and BACE2.


Suppliers

Santa Cruz Biotechnology, Inc.
222304
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CAS equal suppliers

beta-Secretase Inhibitor IV
Santa Cruz Biotechnology, Inc.
sc-222304
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Finipharma Ltd
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beta-Secretase Inhibitor IV
Alpha Biopharmaceuticals Co., Ltd.
AB27548262

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Properties for β-Secretase Inhibitor IV

Molecular Weight:
578.72 g·mol−1
Density:
1.31 g/cm3
Melting point:
103-105° C
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Alternative Distributors of [β-Secretase Inhibitor IV]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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