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Bicine

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Formula: C6H13NO4
CAS: 150-25-4
search Element: bicine
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Identification

Structural Formula
Bicine
CAS:
150-25-4
EINECS:
205-755-1
Molecular Formula:
C6H13NO4
MDL:
MFCD00004295
SMILES:
C(CO)N(CCO)CC(=O)O
Synonym:
diethanolglycine ; bicine ; n,n-dihydroxyethyl ; bicine sigmaultra ; biclne ; diethylolglycine ; bicine, 99+% ; bicine buffer ; bicine ultrapure ; fe-3-specific


Description

Bicine is a zwitterionic amino acid buffer, active in the pH 7.6-9.0 range (pKa of 8.26 at 25°C). Recommended buffer for low temperature biochemical work. Bicine is used for the preparation of stable substrate solution for serum guanase determination. The use of bicine in a thin layer ion exchange chromatography method for protein resolution has been published. Bicine has been utilized in peptide and protein crystallization. A kinetic study of a quaternary transition-state analogue complex of creatine kinase used bicine in the reaction buffer. A multiphasic buffer system for SDS-PAGE of proteins and peptides that incorporates bicine has been described.


Suppliers

Nantong Xindao Biotech Ltd
NXB156624
+
Lori Industry Co., Ltd
LI132396
+
XD BIOCHEMS Ltd
XB90270
+
Krada CPS Industry S.L
KCIS132660
+
Shandong Ench Chemical Co.,Ltd
SECC180900
+
Shandong SanYoung Industry Co., Ltd
SSI210840
+
Sancai Industry Co.,Ltd.
SIC144576
+
Hangzhou Lingrui Chemical Co., Ltd.
HLC210840
+
scienTEST - bioKEMIX GmbH
S-B150600
+
Hangzhou Ocean Chemical Co., Ltd.
HOC198792
+
Zehao Industry Co., Ltd.
ZI144432
+
Leap Chem Co., Ltd
LC108324
+
Santa Cruz Biotechnology, Inc.
216087
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CAS equal suppliers

BICINE, 99%
Alfa (A Johnson Matthey Company)
A3521056
Bicine Ultra
Puyer BioPharma Ltd.
PB4801440
BICINE Ultrapure
Molekula
89697770
BICINE buffer Solution
Santa Cruz Biotechnology, Inc.
291988
N,N-Dihydroxyethylglycine
S. Goldmann GmbH & Co KG
SG12003600
Bicine, 99+%, for biochemistry
Acros Organics BVBA
AOB17106840
n,n-bis(2-hydroxyethyl)glycine
Indofine Chemical Co, Inc.
Bio-071
N,N-Bis(2-hydroxyethyl)glycine
Skyrun Industrial Co., Ltd.
SI32409720
Bicine, Molecular Biology Grade
Santa Cruz Biotechnology, Inc.
sc-363574
Bicine, Molecular Biology Grade
Haihang Industry Co., Ltd.
HI32249672
N,N-bis-(2-Hydroxyethyl)glycine
Contract Chemicals Ltd.
CC28528556
N,N-bis-(2-Hydroxyethyl)glycine
Xingrui Industry Co., Limited
XIL359614384
N,N-bis-(2-Hydroxyethyl)glycine
Gihi Chemicals Co., Limited
GCL334813392
N,N-bis-(2-Hydroxyethyl)glycine
Simagchem Corporation
SC26047812
N,N-bis-(2-Hydroxyethyl)glycine
Shandong Lanhai Industry Co.,Ltd.
SLIC409220460
N,N-bis-(2-Hydroxyethyl)glycine
Xiamen Hisunny Chemical Co., Ltd.
XHC409216368
N,N-bis-(2-Hydroxyethyl)glycine
Xiamen Equation Chemical Co.,Ltd
XECC396819840
N,N-bis-(2-Hydroxyethyl)glycine
Xiamen Kinbester Co., Ltd.
XK32249672
Glycine, n,n-bis(2-hydroxyethyl)-
Angene International Limited
AGN-PC-0JK8PI
N,N-bis-(2-Hydroxyethyl)glycine, Reag.
Serva Electrophoresis GmbH
SE494014820
2-(Bis(2-hydroxyethyl)amino)acetic acid
Ambeed, Inc.
A114701
BICINE (N,N-Bis(2-hydroxyethyl)glycine)
Molekula
12695448
2-[bis-(2-Hydroxyethyl)amino]acetic acid
BLD Pharmatech Ltd
BP432012960
Bicine, 0.2M buffer soln., pH 8.5, low endotoxin
Alfa (A Johnson Matthey Company)
A1075232256
N,N-Di(2-hydroxyethyl)glycine [Good's buffer component for biological research]
TCI Chemicals (India) Pvt. Ltd.
B0484

Prices & Availability




Data is processed


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Properties for Bicine

Molecular Weight:
163.17 g·mol−1
Density:
1.05 g/mL at 20 °C
Melting point:
190 °C (dec.)(lit.)
Boiling point:
361.5-415.5° C at 760 mmHg (Predicted)
Solubility:
H2O: 1 M at 20 °C, clear, colorless
Physical Description:
white/clear crystalline powder
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Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
2-8°C
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Alternative Distributors of [Bicine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Molekula GmbH | ABCR GmbH & Co. KG | LuoYang TianCheng Chemical Reagent Co., Ltd. | Ubichem PLC | Suzhou Rovathin Pharmatech Co., Ltd | Anix-Chem Limited | Jinan Great Chemical Co., Ltd. | Carl Roth GmbH + Co KG | Jinjiangchem Corporation | Discovery Fine Chemicals Limited | BOC Sciences | Jinan Haohua Industry Co., Ltd. | scienTEST

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