8-bromo-cyclic gmp (sodium salt) ; einecs 256-993-8 ; (115974-70-4) 8-aet-cgmp ; guanosine, 8-bromo-,cyclic 3',5'-(hydrogen phosphate), monosodium salt (9ci) ; 8-br-cgmp na ; 8-bromo-cgmp monosodium salt ; 8-bromo-cgmp, sodium salt ; 8-bromoguanosine cyclic3',5'-monophosphate sodium salt ; 8-bromoguanosine-3',5'-cyclophosphate sodium ; 4h-furo[3,2-d]-1,3,2-dioxaphosphorin,guanosine deriv. ; 8-bromo-cgmp sodium ; 8-br-cgmp sodium salt ; br-cgmp, na ; 8-bromo-cgmp na
Description
8-Bromo-cGMP is a cell-permeable cGMP analog with greater resistance to hydrolysis by phosphodiesterases than cGMP. The compound has been shown to preferentially activate cGKIα/β (cGMP-dependent protein kinase). In human platelets, 8-Bromo-cGMP has been found to inhibit thrombin stimulated arachidonic acid release. 8-Bromo-cGMP is known to slow or inhibit intracellular calcium oscillations of tracheal smooth muscle cells in response to acetylcholine.
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