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Busulfan

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Formula: C6H14O6S2
CAS: 55-98-1
search Element: busulfan

Identification

Structural Formula
Busulfan
CAS:
55-98-1
EINECS:
200-250-2
Molecular Formula:
C6H14O6S2
MDL:
MFCD00007562
SMILES:
CS(=O)(=O)OCCCCOS(=O)(=O)C
Synonym:
mitosan ; x149 ; an33501 ; busulfex ; myleran ; mablin ; nsc-750 ; mileran ; gt41 ; mylera


Description

Busulfan is an antineoplastic bifunctional, DNA alkylating agent that causes DNA damage by cross-linking DNA and proteins. Causes double-base lesions mainly at 5'-GA-3' and, to a lesser extent, at 5'-GG-3' sequences. Forms an intrastrand cross-link at the 5'-GA-3' sequence, and to monoalkylation. Induces normal human fibroblast senescence selectively through Erk and p38 pathways.


Suppliers

Ambeed, Inc.
A593389
Aozeal Certified Standards (AOCS), Inc.
B0067.00
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI5522208
X´ian Taicheng Chem Co., Ltd
XTC232928
Hainan Zhongxin Chemical Co., Ltd.
HZC2721088
Aecochem Corp.
AC112336
CSNpharm, Inc.
CSN10512
Hangzhou Lingrui Chemical Co., Ltd.
HLC2801120
Sigma-Aldrich International GmbH
SI256768
AK Scientific, Inc.
AS152456
Leap Chem Co., Ltd
LC144432
Santa Cruz Biotechnology, Inc.
204658
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CAS equal suppliers

Busulfan, 98%
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Hangzhou J&H Chemical Co., Ltd.
HJC20468184
1,4-Butanediol Dimethanesulfonate
TCI Chemicals (India) Pvt. Ltd.
B1022
1,4-Butanediol dimethanesulfonate
Xiamen Equation Chemical Co.,Ltd
XECC211210560
1,4-Butanediol, dimethanesulfonate
Angene International Limited
AGN-PC-09TFVS

Prices & Availability




Data is processed


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Properties for Busulfan

Molecular Weight:
246.3 g·mol−1
Melting point:
114-117 °C(lit.)
Solubility:
Soluble in acetone, 100% ethanol or DMSO; insoluble in water.
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R45 - May cause cancer
R46 - May cause inheritable genetic damage
R63 - Possible risk of harm to the unborn child
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
S7 - Keep container tightly closed
Hazard Classes:
6.1(b)
Hazard Symbols:
T+, T, F
Hazard symbol T Hazard symbol F Hazard symbol T+
Storage temperature :
Hygroscopic, Refrigerator, Under Inert Atmosphere
RID/ADR certification :
UN 2811 6.1 / PG 1
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Alternative Distributors of [Busulfan]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Inter-Chemical Ltd. | Pfaltz & Bauer, Inc. | Jinan Great Chemical Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Xiang Ding Chemical International Co., Ltd | CCS. CHEM. Co., Ltd. | Hallochem Pharma Co., Ltd. | Shandong Tianyu Fine Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Clearsynth Canada INC. | Suzhou Rovathin Pharmatech Co., Ltd | Shanghai AOKChem Group Limited | Jinan Wedo Industrial Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | TRUST&WE Co., Ltd. | Haihang Industry Co., Ltd. | Bichem Lab Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd.

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