Carbamazepine | CAS 298-46-4 | Chemical-Suppliers

Element: carbamazepine

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C-S » Chemicals » carbamazepine-PX78799

Identification

Carbamazepine

CAS:

298-46-4

EINECS:

206-062-7

Molecular Formula:

C₁₅H₁₂N₂O

MDL:

MFCD00005073

SMILES:

C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N

Synonym:

lexin ; carbelan ; epitol ; biston ; g 32883 ; calepsin ; timonil ; sirtal ; tegretol ; neurotol

Description

Carbamazepine is a sodium channel protein inhibitor. Carbamazepine is a compound consisting of a planar ring and is of particular interest in studying sodium channel interactions and cytochrome P450 (CYP). Carbamazepine has been used in the study of sodium channels in neuronal cells. This compound is reported to bind within the inner pore of the sodium channel via affinity binding with the IV-S6 domain. Additionally, Carbamazepine is reported to be a mechanism-based inhibitor of CYP1A2 as this compound contains a planar ring reported to fit within the planar active site of CYP1A2. This compound is also noted to be an in vitro inducer of CYP3A4, the main human metabolizing enzyme present in the liver and intestine.

Suppliers

H&Z Industry Co.,Ltd

HIC2601040

Krada CPS Industry S.L

KCIS2861430

Ambeed, Inc.

A242924

Aozeal Certified Standards (AOCS), Inc.

C0001.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI8973588

Shandong Minglang Chemical Co., Ltd

SMC4551820

Zeta Pharmaceuticals Inc.

ZP325975

Arevipharma GmbH

A208416

Pharma Greven GmbH

PG234702

AXO Industry SA

AIS195780

Hangzhou Verychem Science & Technology Co., Ltd.

HVST6243120

Xiamen Equation Chemical Co.,Ltd

XECC4162080

KHBoddin GmbH

K169338

Hainan Zhongxin Chemical Co., Ltd.

HZC4421768

Aecochem Corp.

AC182546

CSNpharm, Inc.

CSN16283

Hangzhou Keying Chem Co., Ltd.

HKC3901560

Sigma-Aldrich International GmbH

SI4161248

scienTEST - bioKEMIX GmbH

S-B3251300

CM Fine Chemicals

CFC221884

AK Scientific, Inc.

AS247741

Xingrui Industry Co., Limited

XIL3771508

Leap Chem Co., Ltd

LC234702

Santa Cruz Biotechnology, Inc.

202518

Dayang Chem (Hangzhou) Co.,Ltd.

DC4031612

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ACC3001200

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Alfa (A Johnson Matthey Company)

A5761728

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Acros Organics BVBA

AOB3421368

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Santa Cruz Biotechnology, Inc.

sc-217835

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Angene International Limited

AGN-PC-07229O

5H-Dibenz[b,f]azepine-5-carboxamide

BLD Pharmatech Ltd

BP31509450

Prices & Availability

Data is processed

Properties for Carbamazepine

Molecular Weight:

236.27 g·mol−1

Density:

~1.3 g/cm³ (Predicted)

Melting point:

189-192 °C

Boiling point:

~411.0° C at 760 mmHg (Predicted)

Solubility:

Soluble in ethanol (25 mM), acetone, propylene glycol, chloroform (1:10), 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin (29 mg/ml), DMSO (100 mM), methanol, DMF, and ethylene glycol monoethyl ether. Slightly soluble in glacial acetic acid.Insoluble in water.

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R22 - Harmful if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R42/43 - May cause sensitization by inhalation and skin contact

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S22 - Do not breathe dust
S24 - Avoid contact with skin
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S37 - Wear suitable gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Classes:

6.1(b)

Hazard Symbols:

Xn, T, F

Storage temperature :

2-8°C

RID/ADR certification :

3249

Alternative Distributors of [Carbamazepine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified