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20-carboxy Arachidonic Acid

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Formula: C20H30 O4
CAS: 79551-84-1

Identification

Structural Formula
20-carboxy Arachidonic Acid
CAS:
79551-84-1
EINECS:
Molecular Formula:
C20H30 O4
MDL:
SMILES:
C(CCC(=O)O)C/C=CC/C=CC/C=CC/C=CCCCC(=O)O
Synonym:
20-carboxyarachidonic acid ; 20-carboxyarachidonicacid ; 1,20-eicosa-5,8,11,14-tetraenedioic acid ; 5,8,11,14-eicosatetraenedioicacid, (all-z)- ; 5,8,11,14-eicosatetraenedioicacid, (5z,8z,11z,14z)-


Description

20-carboxy arachidonic acid (20-COOH-AA) inhibits ion transport in the kidneys, much like its parent compound 20-HETE. Studies have shown that 20-carboxy arachidonic acid produces vasorelaxation of porcine coronary microvessels constricted with endothelin. Additionally, 20-carboxy arachidonic acid binds to and activates the isolated ligand binding domains of peroxisome proliferator-activated receptor α (PPARα, Kd = 0.87 ± 0.12 µM) and PPARγ (Kd = 1.7 ± 0.5 µM).


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Properties for 20-carboxy Arachidonic Acid

Molecular Weight:
334.45 g·mol−1
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Alternative Distributors of [20-carboxy Arachidonic Acid]

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MSDS:
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