8-bromoguanosine-3',5'-cyclic monophosphorothioate, rp-isomer sodium salt ; 8-bromoguanosine-3'',5''-cyclic monophosphothioate sodium salt rp isomer ; 8-bromoguanosine 3',5'-cyclic monophosphothioate, rp-isomer sodium salt ; 4h-furo[3,2-d]-1,3,2-dioxaphosphorin,guanosine deriv. ; rp-8-bromoguanosine-3',5'-cyclic monophosphorothiote, sodium salt ; guanosine, 8-bromo-,cyclic 3',5'-[hydrogen (r)-phosphorothioate] (9ci) ; 8-bromoguanosine-3',5'-cyclic monophosphorothioate sodium salt, rpisomer ; rp-8-br-cgmps, na ; rp-8-br-cgmps sodium salt ; 8-br-cgmps na, rp-isomer ; 8-bromoguanosino-3',5'-cyclicmonophosphorothioate ; rp-8-br-cgmps ; guanosine,8-bromo-, cyclic 3',5'-(hydrogen phosphorothioate), (r)-
Description
Rp-8-Br-cGMPS is a cell permeable cGMP analog which blocks cGMP-dependent protein kinase. This compound has been shown to suppress sodium nitroprusside-induced luteinizing hormone-releasing hormone (LHRH) secretion from GT1-7 cells. Experiments using isolated rabbit aorta contracted by phenylephrine have shown that Rp-8-Br-cGMPS competitively inhibits relaxation elicited by 8-BR-cGMP. Additionally Rp-8-Br-cGMPS has displayed the capacity to reverse exogenous NO enhanced random migration of peritoneal neutrophils in rabbit models.
Element: 
Chemical-Suppliers.eu