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Clotrimazole

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Formula: C22H17ClN2
CAS: 23593-75-1
search Element: clotrimazole

Identification

Structural Formula
Clotrimazole
CAS:
23593-75-1
EINECS:
245-764-8
Molecular Formula:
C22H17ClN2
MDL:
MFCD00057220
SMILES:
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4
Synonym:
mycelax ; b5097 ; fb5097 ; mycelex ; clt ; canifug ; myclo ; fb 5097 ; bay5097 ; empecid


Description

Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.


Suppliers

Shandong SanYoung Industry Co., Ltd
SSI4201680
Aozeal Certified Standards (AOCS), Inc.
C0008.00
Create Chemical Co., Ltd.
CC300900
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8283312
Shandong Minglang Chemical Co., Ltd
SMC4201680
Lori Industry Co., Ltd
LI264792
Shandong Lanhai Industry Co.,Ltd.
SLIC3961980
H&Z Industry Co.,Ltd
HIC240960
Krada CPS Industry S.L
KCIS2641320
ACIC Fine Chemicals Inc.
AFC2881152
European Manufacturers Assoc. Inc.
EMA4081632
Tessenderlo Chemie
TC216648
CellMark AB
CA132396
Alfa (A Johnson Matthey Company)
A3841152
X´ian Taicheng Chem Co., Ltd
XTC3481392
Xiamen Equation Chemical Co.,Ltd
XECC3841920
Sancai Industry Co.,Ltd.
SIC2881152
Hainan Zhongxin Chemical Co., Ltd.
HZC4081632
Aecochem Corp.
AC168504
Hangzhou Lingrui Chemical Co., Ltd.
HLC4201680
Sigma-Aldrich International GmbH
SI3841152
scienTEST - bioKEMIX GmbH
S-B3001200
Carbone Scientific Co., Ltd.
CS3361008
Hefei Hirisun Pharmatech Co., Ltd
HR130530
Simagchem Corporation
SC252756
Xingrui Industry Co., Limited
XIL3481392
Leap Chem Co., Ltd
LC216648
Santa Cruz Biotechnology, Inc.
3583
Dayang Chem (Hangzhou) Co.,Ltd.
DC3721488
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CAS equal suppliers

Clotrimazole, Pharma
Caesar & Loretz GmbH
CL8002400
clotrimazole crystalline
Hangzhou Yuhao Chemical Technology Co., Ltd
JZ5594
Clotrimazole crystalline
Gihi Chemicals Co., Limited
GCL12965184
1-((2-Chlorophenyl)diphenylmethyl)-(1H)-imidazole
Hangzhou J&H Chemical Co., Ltd.
HJC911436456
1-((2-Chlorophenyl)diphenylmethyl)-(1H)-imidazole
Chemos GmbH & Co. KG
CC588017640
1H-imidazole, 1-[(2-chlorophenyl)diphenylmethyl]-
Angene International Limited
AGN-PC-07A1UI

Prices & Availability




Data is processed


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Properties for Clotrimazole

Molecular Weight:
344.84 g·mol−1
Density:
1.14 g/cm3 (Predicted)
Melting point:
147-149°C
Boiling point:
482.30° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (25 mM), chloroform (50 mg/ml), DMF, ethyl acetate, ethanol, methanol, and acetone.
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
R36/38 - Irritating to eyes and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
Store at RT.
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Alternative Distributors of [Clotrimazole]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Santec Chemicals Corp. | VWR International | Nantong Bestime Chemical Co., Ltd. | Ningbo Zhengrun Chemicals Co., Ltd. Exp. Dept. | Chem-Impex International, Inc. | CCS. CHEM. Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | BioTio Industrial Co., Ltd. | Ningbo Pangs Chem Int'l Co., Ltd. | Changzhou An-Yuan Imp. & Exp. Corporation | Wintersun Chemical | New Dragon Industrial Co., Ltd | Hwasun Pharmaceutical Co.Ltd. | Zibo Panxin Pharmaceutical Co., Ltd. | Discovery Fine Chemicals Limited | Shanghai AOKChem Group Limited | Ningbo Haishu Hobid Imp & Exp Co., Ltd. | Jinan Great Chemical Co., Ltd. | Ningbo Hi-Tech Biochemicals Co., Ltd. | East Chemical Industry Co., Ltd. | Cfm Oskar Tropitzsch GmbH | Watson International Ltd | BOC Sciences | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Jinan Haohua Industry Co., Ltd. | Trademax Phamaceuticals & Chemicals Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC. | scienTEST | Wanko Chemical Co., Ltd. | Haihang Industry Co., Ltd.

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