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Coenzyme A

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Formula: C21H36N7O16P3S
CAS: 85-61-0
search Element: coenzyme

Identification

Structural Formula
Coenzyme A
CAS:
85-61-0
EINECS:
201-619-0
Molecular Formula:
C21H36N7O16P3S
MDL:
MFCD00065465
SMILES:
CC(C)(COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=CN=C3N)O)OP(=O)(O)O)[C@H](C(=O)NCCC(=O)NCCS)O
Synonym:
coa ; coa-sh ; coalip ; lucina ; aluzime ; thiol-coa ; coenzyme a ; conenzyme a ; coenzyme ash ; d-coenzyme a


Description

Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. CoA plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. One of the main functions of CoA is the carrying and transfer of acyl groups. Acylated deriviates, for example acetyl-CoA, are critical intermediates in many metabolic reactions. CoA levels can be altered during starvation, and in conditions such as cancer, diabetes, and alcoholism.

Coenzyme A can bind acetate (Acetyl-CoA) or other carboxylic acids in an energy-rich binding. It is cofactor of many enzyme-catalysed acetylations, e. g. in the citrate cycle (Krebs cycle). For improving the sensitivity of the luciferase assay, CoA is added to the assay buffer at a concentration of 270 μM (2).


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI13805520
Lori Industry Co., Ltd
LI4401320
Unilong Industry Co.,Ltd
UIC4801920
Shandong SanYoung Industry Co., Ltd
SSI7002800
X´ian Taicheng Chem Co., Ltd
XTC5802320
Xiamen Equation Chemical Co.,Ltd
XECC6403200
CSNpharm, Inc.
CSN23682
Finetech Industry Limited
FIL5002000
Xingrui Industry Co., Limited
XIL5802320
Amadis Chemical Company Limited
ACCL6203100
Santa Cruz Biotechnology, Inc.
211123
Chemos GmbH & Co. KG
CC4001200
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Prices & Availability




Data is processed


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Properties for Coenzyme A

Molecular Weight:
767.54 g·mol−1
Solubility:
Soluble in Water.
Physical Description:
yellowish lyophilisate
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Safety & Transport Information

Safety Codes:
S24/25 - Avoid contact with skin and eyes
Storage temperature :
-20°C
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Alternative Distributors of [Coenzyme A]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Acros Organics BVBA | Chem-Impex International, Inc. | Taizhou Chemedir Biopharm-Tech Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Jinan Great Chemical Co., Ltd. | Jinjiangchem Corporation | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Yongyi Chemicals Group Co., Ltd. | Pharmfar Co., Ltd. | BOC Sciences | Hangzhou Ocean Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Skyrun Industrial Co., Ltd. | Pfaltz & Bauer, Inc. | Gihi Chemicals Co., Limited | Xiamen Hisunny Chemical Co., Ltd.

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