Curcumin | CAS 458-37-7 | Chemical-Suppliers

Element: curcumin

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C-S » Chemicals » curcumin-PX1203793

Identification

Curcumin

CAS:

458-37-7

EINECS:

207-280-5

Molecular Formula:

C₂₁H₂₀O₆

MDL:

MFCD00008365

SMILES:

COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O

Synonym:

haidr ; kurkumin ; halad ; haldar ; halud ; yo-kin ; gelbwurz ; curcuma ; curouma ; souchet

Description

Curcumin is a yellow-orange dye obtained from tumeric, the powdered root of Curcuma longa; it is employed in the preparation of curcuma paper, the detection of boron, and possesses a vast number of biological targets. A study investigating the effects of curcumin on reported inflammatory mediators in inflammatory bowel disease on colonic myofibroblasts obtained ex vivo reported that a dose-dependent suppression of matrix metalloproteinase-3 (MMP-3) occured. Curcumin has been shown to inhibit NF-κB, possibly through inhibition of JNK (IC₅₀=10 μM). Curcumin blocks amyloid peptide induced expression of: TNF-α, IL-1β, MCP-1, IL-8, and CCR5, regulates NOS2, inhibits IgE and Ag-induced degranulation of mast cells, inhibits 5-LO (5-lipoxygenase) (IC₅₀=8 μM), Cox-2 (cyclooxygenase-2) (IC₅₀=52 μM), the COP9 signalosome kinase (IC₅₀=10μM), and p300/CREB Binding Protein (p300/CBP). This wide range of activities makes curcumin an extremely useful tool for developing novel analogues and uses. Curcumin is an inhibitor of GST, IKK and NQO1.

Suppliers

Krada CPS Industry S.L

KCIS176880

Fountain Biotechnology Co.,Ltd

FBC240960

Aozeal Certified Standards (AOCS), Inc.

C0093.00

OPQ Chemical Co., Ltd

OC168504

Wuhan PharmChem Co., LTD.

WP200600

Chengdu Pufeide Biotech. Co., Ltd

CPB2641056

Shandong SanYoung Industry Co., Ltd

SSI2801120

Shandong Ench Chemical Co.,Ltd

SECC2401200

Nantong Xindao Biotech Ltd

NXB208832

New Natural Biotechnology Co.,Ltd.

NNBC2721360

Create Chemical Co., Ltd.

CC200600

Lori Industry Co., Ltd

LI176528

Tianjin YR Chemspec Technology Co.,Ltd.

TYCTC3121872

H&Z Industry Co.,Ltd

HIC160640

Ambeed, Inc.

A147405

XD BIOCHEMS Ltd

XB120360

Indofine Chemical Co, Inc.

C-004

C.E. Roeper GmbH

CR128384

Suan Farma, Inc

SFI120480

Fabrichem, Inc.

F120240

Arcadia Biotechnology

AB168504

IBIS Chemie International

ICI200800

Xiamen Equation Chemical Co.,Ltd

XECC2561280

Sancai Industry Co.,Ltd.

SIC192768

Arakato Development Ltd

AD184552

Aecochem Corp.

AC112336

CSNpharm, Inc.

CSN19424

Merck Schuchardt OHG

MSO160640

Hangzhou Keying Chem Co., Ltd.

HKC240960

Sigma-Aldrich International GmbH

SI256768

scienTEST - bioKEMIX GmbH

S-B200800

Finetech Industry Limited

FIL200800

Pharmacore Co., Limited

PL184552

Acinopeptide Co., Ltd.

A176352

CM Fine Chemicals

CFC136544

AK Scientific, Inc.

AS152456

Simagchem Corporation

SC168504

Xingrui Industry Co., Limited

XIL232928

BOC Sciences

BS96288

Leap Chem Co., Ltd

LC144432

Santa Cruz Biotechnology, Inc.

200509

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CAS equal suppliers

Curcurmin

Indenta Chemicals (India) Pvt. Ltd.

IC3151260

Curcumin 98+%

Acros Organics BVBA

AOB247988

Turmeric extract

Tianjin YR Chemspec Technology Co.,Ltd.

TYCTC12487488

Turmeric, natural

SPR Oncocare Pvt Ltd

SOP6802720

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TCI Chemicals (India) Pvt. Ltd.

C0434

curcumin with hplc

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024739S

NANOACTIVE CURCUMIN

Jiwan Pharmaceutical Technology Co., Ltd.

JPT15586232

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TCI Chemicals (India) Pvt. Ltd.

C2302

Curcumin, natural powder

Tianjin YR Chemspec Technology Co.,Ltd.

TYCTC280816848

Curcumin (0.1% in ca. 95% Ethanol)

TCI Chemicals (India) Pvt. Ltd.

C0435

Curcumin, 95% (total curcuminoid content), from Turmeric rhizome

Alfa (A Johnson Matthey Company)

A1433643008

(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

BLD Pharmatech Ltd

BP1085432562

Prices & Availability

Data is processed

Properties for Curcumin

Molecular Weight:

368.38 g·mol−1

Density:

0.93

Melting point:

183 °C

Boiling point:

591.36° C at 760 mmHg (Predicted)

Solubility:

ethanol: 10 mg/mL

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S7 - Keep container tightly closed

Hazard Symbols:

Xi, F

Storage temperature :

-20°C

Alternative Distributors of [Curcumin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified