2-cyano-Pyrimidine | CAS 14080-23-0

Element: pyrimidine cyano

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C-S » Chemicals » cyano-pyrimidine-PX75143

Identification

2-cyano-Pyrimidine

CAS:

14080-23-0

EINECS:

Molecular Formula:

C₅H₃N₃

MDL:

MFCD00160513

SMILES:

C1=CN=C(N=C1)C#N

Synonym:

2cpm ; 2-cpy ; 2-cyanpyrimidine ; 2-cynopyrimidine ; 2-cyanopyrimidine ; 2-cyanopyrimidine ,99% ; 2-cyanopyrimidine, 98+% ; name: 2-cyanopyrimidine ; 2-pyrimidinecarbonitrile ; pyrimidine-2-carbonitrile

Description

2-cyano-Pyrimidine is a cathepsin K inhibitor whose basic structure and subsequent derivatives are under study for the treatment of osteoperosis. Cathepsin K is a lysosomal cysteine protease found in osteoclasts. Elevated activity of this protease has been linked to the formation of osteoporosis and arthritis.

Suppliers

Santa Cruz Biotechnology, Inc.

205083

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Prices & Availability

Data is processed

Properties for 2-cyano-Pyrimidine

Molecular Weight:

105.1 g·mol−1

Density:

~1.2 g/cm³ (Predicted)

Melting point:

40-44 °C(lit.)

Boiling point:

250.67° C at 760 mmHg (Predicted)

Flash point:

>230 ºF

Physical Description:

white to yellow to brown solid

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R22 - Harmful if swallowed
R25 - Toxic if swallowed
R34 - Causes burns
R37/38 - Irritating to respiratory system and skin
R41 - Risk of serious damage to eyes
R43 - May cause sensitisation by skin contact

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Classes:

irritant

Hazard Symbols:

Xn, C, F, T
Hazard symbol T

RID/ADR certification :

3276

Alternative Distributors of [2-cyano-Pyrimidine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified