Cyproterone Acetate | CAS 427-51-0

Element: cyproterone acetate

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C-S » Chemicals » cyproterone-acetate-PX76886

Identification

Cyproterone Acetate

CAS:

427-51-0

EINECS:

207-048-3

Molecular Formula:

C₂₄H₂₉ClO₄

MDL:

MFCD00864671

SMILES:

CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=C(C4=CC(=O)[C@@H]5C[C@@H]5[C@]34C)Cl)C)OC(=O)C

Synonym:

sh-714 ; androcur ; nsc-81430 ; cyprostat ; cyproviron ; cyprosteroneacetate ; cyproteron-racetate ; cyproterone acetate ; cyproferone acetate ; ciproterone acetate

Description

Cyproterone acetate has antagonistic properties towards the androgen receptor (IC₅₀ = 7.1 nM). It can however, also act as a partial agonist of AR (EC₅₀ = 4.0 μM). In the presence of 10 nM testosterone, low concentrations of cyproterone acetate inhibit T-stimulated transcription of 3XHRE-LUC, but at higher concentrations, transcription is stimulated. Cyproterone Acetate is also a hepatomitogen and tumor promoter and induces apoptosis in hepatocytes.

Suppliers

Aozeal Certified Standards (AOCS), Inc.

C0049.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI262210488

Shandong Ench Chemical Co.,Ltd

SECC11405700

H&Z Industry Co.,Ltd

HIC7603040

Shandong SanYoung Industry Co., Ltd

SSI13305320

Ambeed, Inc.

A264009

Crystal Pharma (Gadea Grupo Farmacéutico)

CP15966384

Guangzhou Topwork Chemical Co., Ltd.

GTC13685472

X´ian Taicheng Chem Co., Ltd

XTC11024408

Xiamen Equation Chemical Co.,Ltd

XECC12166080

Aecochem Corp.

AC5321596

CSNpharm, Inc.

CSN10728

Sigma-Aldrich International GmbH

SI12163648

scienTEST - bioKEMIX GmbH

S-B9503800

Carbone Scientific Co., Ltd.

CS10643192

AK Scientific, Inc.

AS7222166

Simagchem Corporation

SC7982394

Xingrui Industry Co., Limited

XIL11024408

Leap Chem Co., Ltd

LC6842052

Santa Cruz Biotechnology, Inc.

204703

Dayang Chem (Hangzhou) Co.,Ltd.

DC11784712

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CAS equal suppliers

Cyprosterone acetate

Hangzhou J&H Chemical Co., Ltd.

HJC12404960

Cyprosterone acetate

Haihang Industry Co., Ltd.

HI10403120

Cyproterone Acetate (Androcur, Cyprostat)

United States Biological

C8940

Prices & Availability

Data is processed

Properties for Cyproterone Acetate

Molecular Weight:

416.94 g·mol−1

Melting point:

200-201°C

Solubility:

Soluble in water (partly), chloroform, methanol (50 mg/ml), DMSO (≥83 mg/ml at 25° C), and ethanol (≥10 mg/ml at 25° C).

Safety & Transport Information

Risk Codes:

R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R40 - Limited evidence of a carcinogenic effect

Safety Codes:

S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Xn, Xi

Storage temperature :

2-8°C

Alternative Distributors of [Cyproterone Acetate]

Producers or manufacturers change the product range from time to time. The following companies
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