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Cytochalasin B

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Formula: C29H37NO5
CAS: 14930-96-2
search Element: cytochalasin

Identification

Structural Formula
Cytochalasin B
CAS:
14930-96-2
EINECS:
239-000-2
Molecular Formula:
C29H37NO5
MDL:
MFCD00077704
SMILES:
C[C@H]1[C@H]2[C@H](CC3=CC=CC=C3)NC(=O)[C@]22OC(=O)C=C[C@H](O)CCC[C@@H](C)CC=C[C@H]2[C@H](O)C1=C
Synonym:
2h-oxacyclotetradecino[2,3-d]isoindole-2,18(5h)-dione,6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-,[5r-(3e,5r*,9r*,11e,12as*,13s*,15s*,15as*,16s*,18as*)]- ; -23-one ; cytochalasin b ; nsc107658 ; cytochalasin b(rg) ; 2h-oxacyclotetradecino[2,3-d]isoindole-2,18(5h)-dione,16-benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-,(e,e)-(5r,9r,12as,13s,15s,15as,16s,18as)- (8ci) ; cytochalasin ; 9r,12as,13s,15s,15as,16as,18as)-5 ; phomin ; 2h-oxacyclotetradecino[2,3-d]isoindole-2,18(5h)-dione,6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-,(3e,5r,9r,11e,12as,13s,15s,15as,16s,18as)- ; cytochalasin b synthetic >97% ; cytochalicinb ; cytochalacinb ; (7s,13e,16r,20r,21e)-0-phenyl ; 24-oxa[14]cytochalasa-6(12),13,21-triene-1,23-dione,7,20-dihydroxy-16-methyl-10-phenyl-, (7s,13e,16r,20r,21e)-


Description

Cytochalasin B is used in actin polymerization studies and cytological research. Cytochalasin B is a metabolite of the fungus Drechslera dematoidea which binds to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. As opposed to other Cytochalasins, cytochalasin A and Cytochalasin B bind to the glucose transporter and inhibit monosaccharide transport across the plasma membrane. Cytochalasin B inhibits phagocytosis by both mononuclear phagocytes and polymorphonuclear leukocytes.


Suppliers

XD BIOCHEMS Ltd
XB4201260
Nantong Xindao Biotech Ltd
NXB7282912
Indofine Chemical Co, Inc.
Bio-733
A.G. Scientific
AS4201260
Serva Electrophoresis GmbH
SE7282184
Finetech Industry Limited
FIL7002800
Leap Chem Co., Ltd
LC5041512
Santa Cruz Biotechnology, Inc.
3519
Dayang Chem (Hangzhou) Co.,Ltd.
DC8683472
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Properties for Cytochalasin B

Molecular Weight:
479.67 g·mol−1
Density:
1.209 g/cm3
Melting point:
218-223 °C
Boiling point:
740.559 °C at 760 mmHg
Flash point:
401.676 °C
Solubility:
ethanol: 20 mg/mL
Physical Description:
white to off-white powder
Transport Information:
UN 1544 6.1/PG 2
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Safety & Transport Information

Risk Codes:
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
R63 - Possible risk of harm to the unborn child
Safety Codes:
S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T+, T
Hazard symbol T Hazard symbol T+
Storage temperature :
-20°C
RID/ADR certification :
UN 1544 6.1 / PG 2
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Alternative Distributors of [Cytochalasin B]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

ABCR GmbH & Co. KG | Jinan Great Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Cfm Oskar Tropitzsch GmbH | Yongyi Chemicals Group Co., Ltd. | BioBioPha Co., Ltd. | Fermentek Ltd. | Clearsynth Canada INC.

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