Daptomycin | CAS 103060-53-3 | Chemical-Suppliers

Element: daptomycin

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C-S » Chemicals » daptomycin-PX74981

Identification

Daptomycin

CAS:

103060-53-3

EINECS:

Molecular Formula:

C₇₂H₁₀₁N₁₇O₂₆

MDL:

MFCD08282794

SMILES:

CCCCCCCCCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]1[C@@H](C)OC(=O)[C@H](CC(=O)C2=CC=CC=C2N)NC(=O)[C@@H](NC(=O)[C@@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)CNC1=O)[C@H](C)CC(O)=O

Synonym:

cubicin daptomycin ; daptomycine ; daptomycin, >=99% ; n-[n-decanoyl-l-trp-d-asn-l-asp-]-cyclo[thr*-gly-l-orn-l-asp-d-ala-l-asp-gly-d-ser-[(3r)-3-methyl-l-glu-]-3-(2-aminobenzoyl)-l-ala-] ; n-(n-decanoyl-l-trp-d-asn-l-asp-)cyclo[l-thr*-gly-l-orn-l-asp-d-ala-l-asp-gly-d-ser-[(3r)-3-methyl-l-glu-]-3-(2-aminobenzoyl)-l-ala-] ; dapcin ; cidecin ; ly-146032 ; daptomycin ; cubicin

Description

Daptomycin is a lipopeptide antibiotic produced by Streptomyces roseosporus with reported in vitro bactericidal activity against gram-positive organisms. As a calcium-dependent antibiotic, Daptomycin has been reported to act on the cytoplasmic membrane and undergo a conformational change upon interaction with lipid membranes in a model system. After the conformational change occurs, the compound is inserted into the membrane and causes significant perturbations. Membrane depolarization and leakage occurs, causing death in susceptible organisms.

Suppliers

H&Z Industry Co.,Ltd

HIC200800

Shandong SanYoung Industry Co., Ltd

SSI3501400

Nantong Xindao Biotech Ltd

NXB2601040

Aozeal Certified Standards (AOCS), Inc.

D0063.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6902760

Lori Industry Co., Ltd

LI220660

JieJie Group Co., Ltd.

JG220660

Chemvon Biotechnology Co. Ltd.

CBC3001200

X´ian Taicheng Chem Co., Ltd

XTC2901160

BoomKing Industrial Co.,Limited

BIC3101240

Xiamen Equation Chemical Co.,Ltd

XECC3201600

Aecochem Corp.

AC140420

CSNpharm, Inc.

CSN16684

Hangzhou Keying Chem Co., Ltd.

HKC3001200

Hangzhou Lingrui Chemical Co., Ltd.

HLC3501400

Wanko Chemical Co., Ltd.

WC240720

Finetech Industry Limited

FIL2501000

Pharmacore Co., Limited

PL230690

AK Scientific, Inc.

AS190570

Xingrui Industry Co., Limited

XIL2901160

BOC Sciences

BS120360

Amadis Chemical Company Limited

ACCL3101550

Leap Chem Co., Ltd

LC180540

Santa Cruz Biotechnology, Inc.

202125

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Prices & Availability

Data is processed

Properties for Daptomycin

Molecular Weight:

1620.68 g·mol−1

Density:

~1.5 g/cm³ (Predicted)

Melting point:

202-204 °C C

Boiling point:

~2078.22° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (100 mg/ml at 25° C), ethanol (50 mM), methanol (5 mg/ml), DMSO (100 mM), and DMF.

Safety & Transport Information

Storage temperature :

Store at -20 °C

Alternative Distributors of [Daptomycin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified