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N-Deacetylcolchicine

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Formula: C20H23NO5
CAS: 3476-50-4
search Element: deacetylcolchicine
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Identification

Structural Formula
N-Deacetylcolchicine
CAS:
3476-50-4
EINECS:
Molecular Formula:
C20H23NO5
MDL:
MFCD00278752
SMILES:
COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)N
Synonym:
(7s)-7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-benzo[a]heptalen-9(5h)-one ; (-)-7-deacetylcolchicine ; nsc 201400 ; trimethylcolchicinic acid methyl ether ; 7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-benzo[a]heptalen-9(5h)-one ; (s)-n-deacetyl colchicine ; desacetylcolchicine ; (s)-7-amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5h)-one ; deacetylcolchicine


Description

Antimitotic agent that intercepts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signal.


Suppliers

Santa Cruz Biotechnology, Inc.
219099
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CAS equal suppliers

(S)-N-Deacetyl Colchicine
Pharmaffiliates Analytics & Synthetics Pvt. Limited
PA 03 74520

Prices & Availability




Data is processed


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Properties for N-Deacetylcolchicine

Molecular Weight:
357.40 g·mol−1
Density:
~1.3 g/cm3 (Predicted)
Melting point:
80-85° C
Boiling point:
~626.6° C at 760 mmHg (Predicted)
Solubility:
Soluble in chloroform, dichloromethane, DMSO, methanol, and water (6.54 g/l).
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Safety & Transport Information

Storage temperature :
-20 °C Freezer, Under Inert Atmosphere
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Alternative Distributors of [N-Deacetylcolchicine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

3B Scientific Corporation | Chengdu Qiaofeng Technological Development Co., Ltd. | Clearsynth Canada INC.

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Downloads

Mol File:
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MSDS:
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