Identification
Dibenzazepine (Deshydroxy LY 411575)
Molecular Formula:
C2 6 H2 3 F2 N3 O3
SMILES:
C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)CC4=CC(=CC(=C4)F)F
Synonym:
yo-01027 (dibenzazepine) ; γ-secretase inhibitor dbz ; dibenzazepine ; (s)-2-(2-(3,5-difluorophenyl)acetamido)-n-((s)-5-methyl-6-oxo-6,7-dihydro-5h-dibenzo[b,d]azepin-7 ; deshydroxy ly-411575 ; 7-(s)-[n'(3,5-difluorophenylacetyl)-l-alaninyl]amino-5-methyl-5,7-dihydro-6h-dibenz[b,d]azepin-6-one ; gsi-xx ; dibenzazepine (deshydroxy ly 411575) ; yo-01027/dibenzazepine/ly 411575 ; γ-secretase inhibitor xx
Description
Dibenzazepine (Deshydroxy LY 411575) is a dipeptidic γ-secretase inhibitor which potently blocks Notch processing. It is also known as an anti-Alzheimer agent.
Suppliers
CM Fine Chemicals
CFC18367344
Amadis Chemical Company Limited
ACCL334816740
Santa Cruz Biotechnology, Inc.
207554
CAS equal suppliers
YO01027
Excenen Pharmatech Co., Ltd.
EX-A027
YO-01027
ShangHai Biochempartner Co., Ltd.
BCP02556
YO-01027
CSNpharm, Inc.
CSN13122
Dibenzazepine
Salsbury Chemicals, Inc.
SC312936
Dibenzazepine
Aea.ltd
A91182
gamma-Secretase Inhibitor XX
Alfa (A Johnson Matthey Company)
A26888064
gamma-Secretase Inhibitor XX
Alpha Biopharmaceuticals Co., Ltd.
AB28568568
(S)-2-(2-(3,5-Difluorophenyl)acetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propanamide
Hangzhou MolCore BioPharmatech Co.,Ltd.
MC100601
N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Leap Chem Co., Ltd
LC45360136080
Prices & Availability
Data is processed
Properties
Safety & Transport
Alternative Distributors
Downloads
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Properties for Dibenzazepine (Deshydroxy LY 411575)
Molecular Weight:
463.48 g·mol−1
Melting point:
257-259 °C C
Boiling point:
~801.3° C at 760 mmHg (Predicted)
Solubility:
Soluble in chloroform, methanol, DMSO (93 mg/ml at 25° C), water (<1 mg/ml at 25° C), and ethanol (<1 mg/ml at 25° C).
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Safety & Transport Information
Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
Hazard Symbols:
Xi
Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Dibenzazepine (Deshydroxy LY 411575)]
Producers or manufacturers change the product range from time to time.
Currently there are no other manufacturers known.
Element: 
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