5(S),12(R)-DiHETE(6-trans-LTB4) | CAS 71652-82-9

Element: dihete trans ltb4

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C-S » Chemicals » dihete-trans-ltb-PX65247

Identification

5(S),12(R)-DiHETE(6-trans-LTB4)

CAS:

71652-82-9

EINECS:

Molecular Formula:

C₂₀H₃₂ O₄

MDL:

MFCD00065850

SMILES:

CCCCC/C=CC[C@@H](O)/C=C/C=C/C=C/[C@@H](O)CCCC(=O)O

Synonym:

6-trans-leukotriene b4 ; (6e,5s,12r)-leukotriene b4 ; leukotriene b4, trans-6 ; 5(s),12(r)-dihydroxy-6,8,10,14-(trans,trans,trans,cis)-eicosatetraenoic acid ; 5(s), 12(r)-dihete ; 6-trans leukotriene b4 lipid maps ms standard ; all trans ltb4 ; 5s,12r-dihydroxy-6e,8e,10e,14z-eicosatetraenoic acid ; 6-trans-ltb4 ; trans-6-leukotriene b4 ; 6-trans leukotriene b4 ; d6-trans-leukotriene b4 ; 6,8,10,14-eicosatetraenoicacid, 5,12-dihydroxy-, (5s,6e,8e,10e,12r,14z)- ; 5(s),12(r)-dihete(6-trans-ltb4) ; d6-trans-ltb4 ; trans-6-leukotriene b4 solution ; 6,8,10,14-eicosatetraenoicacid, 5,12-dihydroxy-, [s-[r*,s*-(e,e,e,z)]]-

Description

5(S),12(R)-DiHETE(6-trans-LTB4) belongs to Leukotrienes. Leukotrienes comprise a family of endogenous metabolites of certain fatty acids and are related to thromboxanes and prostaglandins. They are potent eicosanoid lipid mediators that play numerous roles in inflammation, immunological functions and maintaining biological homeostasis. Leukotrienes possess a conjugated triene structure which gives them their name. They are generally isolated from leukocytes and primarily act through specific G protein-coupled receptors. Biosynthesis of 5(S),12(R)-DiHETE(6-trans-LTB4) has been shown to occur via nonenzymatic and enzymatic hydrolysis of LTA4 and by myeloperoxidase-dependent metabolism of cysteinyl leukotrienes. Observations indicate that it is a neutrophil chemotaxin in guinea pig dermis and a metabolite of LTB4 in rat kidney produced enzymatically by a novel isomerase reaction.

Suppliers

Santa Cruz Biotechnology, Inc.

200423

Santa Cruz Biotechnology, Inc.

sc-200423

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Data is processed

Properties for 5(S),12(R)-DiHETE(6-trans-LTB4)

Molecular Weight:

336.47 g·mol−1

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

F, Xi

Storage temperature :

?20 °C

Alternative Distributors of [5(S),12(R)-DiHETE(6-trans-LTB4)]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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