Dihydro-D-erythro-Sphingosine | CAS 764-22-7

Element: sphingosine dihydro erythro

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C-S » Chemicals » dihydro-erythro-sphingosine-PX72595

Identification

Dihydro-D-erythro-Sphingosine

CAS:

764-22-7

EINECS:

Molecular Formula:

C₁₈H₃₉ N O₂

MDL:

MFCD07371371

SMILES:

CCCCCCCCCCCCCCCC(C(CO)N)O

Synonym:

erythro-sphinganine ; octadecasphinganine ; (2s,3r)-2-azanyloctadecane-1,3-diol ; d-erythro-1,3-dihydroxy-2-aminooctadecane ; (2s,3r)- ; d-erythro-c18-dihydro-d-sphingosine ; spc-102860 ; c18-dihydrosphingosine ; 1,3-octadecanediol, 2-amino-, [r-(r*,s*)]- ; spc 102860 ; c18-sphingosine, dihydro- ; d-erythro-c18-dihydrosphingosine ; d-erythro-dihydro-d-sphingosine ; 1,3-octadecanediol,2-amino-, d-erythro- (8ci) ; (2s,3r)-2-aminooctadecane-1,3-diol ; dihydrosphingosine ; d-erythro-2-amino-1,3-octadecanediol ; dihydro-c18-sphingosine ; dihydro-d-erythro-sphingosine ; sphinganine ; d-erythro-sphinganine ; 1,3-octadecanediol,2-amino-, (2s,3r)- ; d-erythro-sphinganine

Description

Dihydro-D-erythro-Sphingosine is a biosynthetic precursor of sphingosine that inhibits PKC (protein kinase C) in Chinese hamster ovary cells (IC₅₀ = 2.8 μM). Dihydro-D-erythro-Sphingosine also directly inhibits PLA2 (phospholipase A2) and PC-PLD (phospholipase D). Dihydro-D-erythro-Sphingosine is a substrate of SphK.