10,11-Dihydro-10-hydroxy carbamazepine | CAS 29331-92-8

Element: carbamazepine dihydro hydroxy

Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification Properties Suppliers Prices & Availability Get Quick Quote

C-S » Chemicals » dihydro-hydroxy-carbamazepine-PX81188

Identification

10,11-Dihydro-10-hydroxy carbamazepine

CAS:

29331-92-8

EINECS:

Molecular Formula:

C₁₅H₁₄ N₂ O₂

MDL:

MFCD00871817

SMILES:

C1C(C2=CC=CC=C2N(C3=CC=CC=C31)C(=O)N)O

Synonym:

gp 47779 ; licarbazepine see 16178912 ; 10,11-dihydro-10-hydroxy-5h-dibenz[b,f]azepine-5-carboxamide ; 10-hydroxy-10,11-dihydrocarbamazepine ; hydroxycarbamazepine ; 10-hydroxy-10,11-dihydrocarbamezepine ; gp 47779-d3 ; 10,11-dihydro-10-hydroxycarbazepine-d3 ; licarbazepine ; bia 2-005-d3 ; 10,11-dihydro-10-hydroxy ; bia 2-005 ; 10,11-dihydro-10-hydroxycarbamazepine

Description

10,11-Dihydro-10-hydroxy Carbamazepine is an oxcarbazepine metabolite which induces microsomal enzymes in hepatocytes via sodium channel protein inhibition. Identification techniques such as liquid chromatography-tandem mass spectrometry is used to quantify 10,11-Dihydro-10-hydroxy Carbamazepine in human plasma. In addition, 10,11-Dihydro-10-hydroxy Carbamazepine promotes the release of hippocampal monoamines and produces a dose-dependent inhibition of glutamatergic excitatory postsynaptic potentials (EPSPs) of rat striatum. Furthermore, 10,11-Dihydro-10-hydroxy Carbamazepine reduces calcium ion concentration via a decrease in high-voltage-activated (HVA) Ca2+ currents evoked by membrane depolarization which is independent of dihydropyridine-sensitive channels.

Suppliers

Aozeal Certified Standards (AOCS), Inc.

O0006.02

AK Scientific, Inc.

AS21666498

Santa Cruz Biotechnology, Inc.

206270

Dayang Chem (Hangzhou) Co.,Ltd.

DC353414136

Get Quick Quote

CAS equal suppliers

licarbazepine

Hangzhou MolCore BioPharmatech Co.,Ltd.

MC425457

Licarbazepine

Leap Chem Co., Ltd

LC234702

Licarbazepine

Finipharma Ltd

F182364

Carbamazepine Impurity 1

Aozeal Certified Standards (AOCS), Inc.

C0001.08

10,11-Dihydro-10-hydroxycarbamazepine

Hangzhou Trylead Chemical Technology Co., Ltd.

HTCT340417020

10,11-Dihydro-10-hydroxycarbamazepine

CM Fine Chemicals

CFC12585032

10,11-Dihydro-10-hydroxycarbamazepine

Sigma-Aldrich International GmbH

SI23687104

10-Hydroxy-10,11-dihydro-5hdibenzo[b,f]azepine-5-carboxamide

BLD Pharmatech Ltd

BP756022680

10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

Ambeed, Inc.

A334944

5H-dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-

Angene International Limited

AGN-PC-07A1XA

(±)-10-Hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide

Hangzhou Yuhao Chemical Technology Co., Ltd

LX2341

Prices & Availability

Data is processed

Properties for 10,11-Dihydro-10-hydroxy carbamazepine

Molecular Weight:

254.28 g·mol−1

Density:

1.336 g/cm3

Melting point:

186-189°C

Boiling point:

431.3°C at 760 mmHg

Flash point:

214.6°C

Solubility:

Soluble in Chloroform, Dimethyl Sulfoxide and Ethanol

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36 - Irritating to eyes
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet

Hazard Symbols:

N, Xn, F

Storage temperature :

Store at RT

Alternative Distributors of [10,11-Dihydro-10-hydroxy carbamazepine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Synfine Research Inc. | Clearsynth Canada INC.