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Diphenyleneiodonium chloride

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Formula: C12H8ICl
CAS: 4673-26-1

Identification

Structural Formula
Diphenyleneiodonium chloride
CAS:
4673-26-1
EINECS:
Molecular Formula:
C12H8ICl
MDL:
MFCD00214165
SMILES:
C1=CC=C2C(=C1)C3=CC=CC=C3[I+]2.[Cl-]
Synonym:
dpi chloride ; dibenz[b,d]iodolium chloride ; [1,1'-biphenyl]-2,2'-diyliodonium chloride ; diphenyleneiodonium chloride, 97+% 25mg ; diphenyleneiodonium chloride ; dibenziodolium chloride ; diphenyleneiodonium chloridedibenziodolium chloride ; diphenyleneiodonium chloride, 97+% ; dibenziodolium chloride, dpi ; dpi


Description

Diphenyleneiodonium chloride has been shown to be a potent irreversible inhibitor of NOS2 (iNOS) from macrophages and NOS3 (eNOS) from endothelial cells. It has also been used to inhibit other flavoenzymes such as neutrophil NADPH oxidase and to bind strongly to flavoproteins. It is thus a powerful and specific inhibitor of several important enzymes, including NADPH cytochrome P450 oxidoreductase, NADPH oxidases and NADPH-ubiquinone oxidoreductase.


Suppliers

A.G. Scientific
AS8402520
Amadis Chemical Company Limited
ACCL17368680
Leap Chem Co., Ltd
LC10083024
Santa Cruz Biotechnology, Inc.
202584
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CAS equal suppliers

Dibenziodolium, chloride
Angene International Limited
AGN-PC-0KK636

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Properties for Diphenyleneiodonium chloride

Molecular Weight:
314.55 g·mol−1
Melting point:
312-322 °C
Solubility:
Soluble in water (0.2 mg/ml), DMSO (with strong heating, 10 mg/ml), ethanol (0.2 mg/ml), H2O:DMSO (40:60, 2.94 mg/ml), and H2O:DMSO (10:90, 9.09 mg/ml).
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Safety & Transport Information

Risk Codes:
R36 - Irritating to eyes
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
-20°C
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Alternative Distributors of [Diphenyleneiodonium chloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Hebei Oxen Special Chemicals Company Limited

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MSDS:
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