DPO-1 | CAS 43077-30-1 | Chemical-Suppliers

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C-S » Chemicals » dpo-PX78680

Identification

DPO-1

CAS:

43077-30-1

EINECS:

Molecular Formula:

C₂₂H₂₉OP

MDL:

MFCD09038567

SMILES:

C[C@@H]1CC[C@H]([C@H](C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3)C(C)C

Synonym:

[1s-(1?,2?,5?)]-[5-methyl-2-(1-methylethyl)cyclohexyl]diphenylphosphineoxide ; (+)-neomenthyl diphenylphosphine oxide ; (1s,2s,5r)-5-methyl-2-(1-methylethyl)cyclohexyl]diphenyl-phosphine oxide ; dpo-1

Description

DPO-1 is a blocker of Kv1.5 channel and IK_ur ultrarapid delayed rectifier potassium current. (IC₅₀ = 0.31 μM for rKV1.5). Displays selectivity for inhibition of IK_ur over I_to (8-fold), IK₁, IK_r and IK_s (20-fold) in native myocytes and selectivity for rat recombinanant KV1.5 over KV3.1 (~ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia.

Suppliers

Aea.ltd

A3570

Santa Cruz Biotechnology, Inc.

203570

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Prices & Availability

Data is processed

Properties for DPO-1

Molecular Weight:

340.444 g·mol−1

Density:

~1.1 g/cm³ (Predicted)

Melting point:

85.25° C (Predicted)

Boiling point:

~434.97° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (>5 mg/ml at ~60° C), and ethanol (100 mM).

Safety & Transport Information

Storage temperature :

Store at +4°C

Alternative Distributors of [DPO-1]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

East Chemical Industry Co., Ltd.

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MSDS:

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