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Dynamin Inhibitor I, Dynasore

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Formula: C18H14N2O4H2O
CAS: 304448-55-3
search Element: inhibitor dynasore dynamin
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Identification

Structural Formula
Dynamin Inhibitor I, Dynasore
CAS:
304448-55-3
EINECS:
Molecular Formula:
C18H14N2O4H2O
MDL:
MFCD11045288
SMILES:
C1=CC=C2C=C(C(=CC2=C1)C(=O)NN/C=C/3C=CC(=O)C(=C3)O)O
Synonym:
(e)-3-hydroxy-n'-((3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl)-2-naphthohydrazide ; dynasore monohydrate ; n'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide ; dynasore ; 3-hydroxynaphthalene-2-carboxylicacid(3,4-dihydroxybenzylidene)hydrazide ; 3-hydroxy-2-naphthalenecarboxylic acid [(3,4-dihydroxyphenyl)methylene]hydrazide dynasore ; dynasore, >=98% ; 3-hydroxy-2-naphthalenecarboxylic acid [(3,4-dihydroxyphenyl)methylene]hydrazide ; 2-naphthalenecarboxylic acid, 3-hydroxy-, 2-[(3,4-dihydroxyphenyl)methylene]hydrazide ; dynamin inhibitor i, dynasore


Description

Dynasore is a non-competitive, cell-permeable semicarbazone compound inhibitor of Dynamin I and Dynamin II. Members of the Dynamin family, including Dynamin I, Dynamin II and Dynamin III, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Dynasore acts as a potent inhibitor of endocytic pathways known to depend on dynamin by blocking coated vesicle formation. Dynamin Inhibitor I, Dynasore is an inhibitor of DRP1.


Suppliers

Santa Cruz Biotechnology, Inc.
202592
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Prices & Availability




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Properties for Dynamin Inhibitor I, Dynasore

Molecular Weight:
322.31 g·mol−1
Density:
~1.4 g/cm3 (Predicted)
Melting point:
251.04° C (Predicted)
Solubility:
Soluble in DMSO (100 mM), and ethanol (5 mM). Insoluble in water.
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Safety & Transport Information

Risk Codes:
R50 - Very toxic to aquatic organisms
Safety Codes:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
Hazard Symbols:
N
Hazard symbol N
Storage temperature :
-20°C
RID/ADR certification :
UN 3077 9 / PG 3
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Alternative Distributors of [Dynamin Inhibitor I, Dynasore]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Mol File:
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MSDS:
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