Ebselen | CAS 60940-34-3 | Chemical-Suppliers

Element: ebselen

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C-S » Chemicals » ebselen-PX79061

Identification

Ebselen

CAS:

60940-34-3

EINECS:

Molecular Formula:

C₁₃H₉NOSe

MDL:

MFCD00210937

SMILES:

C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2

Synonym:

ebselen 99% ; spi-1005 ; dr-3305 ; nsc 639762 ; pz51 ; ebselen ; harmokisane ; ebselen,99% ; ccg-39161 ; rp-60931

Description

Ebselen is an interesting organoselenium compound displaying antiinflammatory and antioxidant properties. Ebselen is shown to inhibit the 5-lipoxygenase (5-LO) and 15-lipoxygenase (15-LO) enzymes in the absence of glutathione. Ebselen also inhibits Cox (cyclooxygenase), PKC (protein kinase C), DECR1 (NADPH), and Mox-1 (NADPH oxidase). The oxidation of low density lipoproteins by free radicals is suppressed by the antioxidant action of Ebselen. Ebselen is an inhibitor of Cox-1, Cox-2, NOS, GST and IDO.

Suppliers

Ambeed, Inc.

A121080

Aea.ltd

A4998

A.G. Scientific

AS105315

CSNpharm, Inc.

CSN10885

Pharmacore Co., Limited

PL161483

AK Scientific, Inc.

AS133399

BOC Sciences

BS84252

Leap Chem Co., Ltd

LC126378

Santa Cruz Biotechnology, Inc.

200740

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CAS equal suppliers

2-Phenyl-1,2-benzoselenazol-3-one

Manchester Organics Limited

K98593

2-Phenyl-1,2-benzisoselenazol-3(2H)-one

BLD Pharmatech Ltd

BP28088424

2-Phenylbenzo[d][1,2]selenazol-3(2H)-one

Hangzhou MolCore BioPharmatech Co.,Ltd.

MC100752

1,2-Benzisoselenazol-3(2h)-one, 2-phenyl-

Angene International Limited

AGN-PC-09O84Y

Prices & Availability

Data is processed

Properties for Ebselen

Molecular Weight:

274.18 g·mol−1

Melting point:

178-181 °C

Boiling point:

~402.8° C at 760 mmHg (Predicted)

Solubility:

Soluble in PBS pH7.2, DMSO (25 mg/ml), ethanol (10 mg/ml), methanol, acetone, acetonitrile, and DMF (~5 mg/ml).

Safety & Transport Information

Risk Codes:

R23/25 - Toxic by inhalation and if swallowed
R33 - Danger of cumulative effects
R36/37/38 - Irritating to eyes, respiratory system and skin
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment

Safety Codes:

S20/21 - When using do not eat, drink or smoke
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S60 - This material and its container must be disposed of as hazardous waste
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet

Hazard Symbols:

T, N, Xi

Storage temperature :

2-8°C

RID/ADR certification :

UN 3283 6.1 / PG 3

Alternative Distributors of [Ebselen]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

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MSDS:

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